1a2y

HEN EGG WHITE LYSOZYME, D18A MUTANT, IN COMPLEX WITH MOUSE MONOCLONAL ANTIBODY D1.3

Authors	Dall'Acqua, W. Goldman, E.R. Lin, W. Teng, C. Tsuchiya, D. Li, H. Ysern, X. Braden, B.C. Li, Y. Smith-Gill, S.J. Mariuzza, R.A.
Citation	A mutational analysis of binding interactions in an antigen-antibody protein-protein complex.
Release date	2003-04-01
Exp. Method	X-RAY DIFFRACTION
Resolution	1.5 Å
Classification	COMPLEX (IMMUNOGLOBULIN/HYDROLASE)

Sequence

Chain A (107 residues): Blast Uniprot

DIVLTQSPASLSASVGETVTITCRASGNIHNYLAWYQQKQGKSPQLLVYYTTTLADGVPSRFSGSGSGTQYSLKINSLQP
EDFGSYYCQHFWSTPRTFGGGTKLEIK

Chain B (116 residues): Blast Uniprot

QVQLQESGPGLVAPSQSLSITCTVSGFSLTGYGVNWVRQPPGKGLEWLGMIWGDGNTDYNSALKSRLSISKDNSKSQVFL
KMNSLHTDDTARYYCARERDYRLDYWGQGTTLTVSS

Chain C (129 residues): Blast Uniprot EC 3.2.1.17

KVFGRCELAAAMKRHGLANYRGYSLGNWVCAAKFESNFNTQATNRNTDGSTDYGILQINSRWWCNDGRTPGSRNLCNIPC
SALLSSDITASVNCAKKIVSDGNGMNAWVAWRNRCKGTDVQAWIRGCRL