1ao8

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1ao8

DIHYDROFOLATE REDUCTASE COMPLEXED WITH METHOTREXATE, NMR, 21 STRUCTURES

Authors Gargaro, A.R. Soteriou, A. Frenkiel, T.A. Bauer, C.J. Birdsall, B. Polshakov, V.I. Barsukov, I.L. Roberts, G.C. Feeney, J.
Citation The solution structure of the complex of Lactobacillus casei dihydrofolate reductase with methotrexate.
Release date 1998-02-25
Exp. Method NMR
Resolution 0.0 Å
Classification OXIDOREDUCTASE

Sequence

Chain A (162 residues): Blast Uniprot EC 1.5.1.3
TAFLWAQDRDGLIGKDGHLPWHLPDDLHYFRAQTVGKIMVVGRRTYESFPKRPLPERTNVVLTHQEDYQAQGAVVVHDVA
AVFAYAKQHPDQELVIAGGAQIFTAFKDDVDTLLVTRLAGSFEGDTKMIPLNWDDFTKVSSRTVEDTNPALTHTYEVWQK
KA


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