1au7
From PDBWiki
PIT-1 MUTANT/DNA COMPLEX
| Authors | Jacobson, E.M. Li, P. Leon-del-Rio, A. Rosenfeld, M.G. Aggarwal, A.K. |
| Citation | Structure of Pit-1 POU domain bound to DNA as a dimer: unexpected arrangement and flexibility. PubMed |
| Release date | 2003-04-01 |
| Exp. Method | X-RAY DIFFRACTION |
| Resolution | 2.3 Å |
| Classification | TRANSCRIPTION/DNA |
Sequence
Chain A (146 residues): Blast UniprotGMRALEQFANEFKVRRIKLGYTQTNVGEALAAVHGSEFSQTTICRFENLQLSFKNACKLKAILSKWLEEAEQVGALYNEK VGANERKRKRRTTISIAAKDALERHFGEHSKPSSQEIMRMAEELNLEKEVVRVWFCNRRQREKRVKChain B (146 residues): Blast Uniprot
GMRALEQFANEFKVRRIKLGYTQTNVGEALAAVHGSEFSQTTICRFENLQLSFKNACKLKAILSKWLEEAEQVGALYNEK VGANERKRKRRTTISIAAKDALERHFGEHSKPSSQEIMRMAEELNLEKEVVRVWFCNRRQREKRVKChain C (25 residues): Blast
TCCTCATGTATATACATGAGGAAGGChain D (24 residues): Blast
CTTCCTCATGTATATACATGAGGA
User comments
Unusual geometry
It is interesting to look at this structure in contrast to 1hf0 and 1e3o. The relative 'geometry' of the two DNA binding domains in the two subunits is unusual. See also 1cqt and 2d5v.
On this page you can see an experimental summary (overview) of the set of structures linked from this page (the above structures).
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