1auj

From PDBWiki

Authors	Lee, S.L. Alexander, R.S. Smallwood, A. Trievel, R. Mersinger, L. Weber, P.C. Kettner, C.
Citation	New inhibitors of thrombin and other trypsin-like proteases: hydrogen bonding of an aromatic cyano group with a backbone amide of the P1 binding site replaces binding of a basic side chain.
Release date	1998-10-14
Exp. Method	X-RAY DIFFRACTION
Resolution	2.1 Å
Classification	HYDROLASE

Sequence

Chain A (223 residues): Blast Uniprot EC 3.4.21.4

IVGGYTCGANTVPYQVSLNSGYHFCGGSLINSQWVVSAAHCYKSGIQVRLGEDNINVVEGNEQFISASKSIVHPSYNSNT
LNNDIMLIKLKSAASLNSRVASISLPTSCASAGTQCLISGWGNTKSSGTSYPDVLKCLKAPILSDSSCKSAYPGQITSNM
FCAGYLEGGKDSCQGDSGGPVVCSGKLQGIVSWGSGCAQKNKPGVYTKVCNYVSWIKQTIASN

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