1b2s

STRUCTURAL RESPONSE TO MUTATION AT A PROTEIN-PROTEIN INTERFACE

Authors	Vaughan, C.K. Buckle, A.M. Fersht, A.R.
Citation	Structural response to mutation at a protein-protein interface.
Release date	2004-02-24
Exp. Method	X-RAY DIFFRACTION
Resolution	1.82 Å
Classification	HYDROLASE/HYDROLASE INHIBITOR

Sequence

Chain A (110 residues): Blast Uniprot EC 3.1.27.-

AQVINTFDGVADYLQTYHKLPDNYITASEAQALGWVASKGNLADVAPGKSIGGDIFSNREGKLPGKSGRTWREADINYTS
GFRNSDRILYSSDWLIYKTTDHYQTFTKIR

Chain B (110 residues): Blast Uniprot EC 3.1.27.-

AQVINTFDGVADYLQTYHKLPDNYITASEAQALGWVASKGNLADVAPGKSIGGDIFSNREGKLPGKSGRTWREADINYTS
GFRNSDRILYSSDWLIYKTTDHYQTFTKIR

Chain C (110 residues): Blast Uniprot EC 3.1.27.-

AQVINTFDGVADYLQTYHKLPDNYITASEAQALGWVASKGNLADVAPGKSIGGDIFSNREGKLPGKSGRTWREADINYTS
GFRNSDRILYSSDWLIYKTTDHYQTFTKIR

Chain D (90 residues): Blast Uniprot

MKKAVINGEQIRSISDLHQTLKKELALPEYYGENLDALWDCLAGWVEYPLVLEWRQFEQSKQLTENGAESVLQVFREAKA
EGCDITIILS

Chain E (90 residues): Blast Uniprot

MKKAVINGEQIRSISDLHQTLKKELALPEYYGENLDALWDCLAGWVEYPLVLEWRQFEQSKQLTENGAESVLQVFREAKA
EGCDITIILS

Chain F (90 residues): Blast Uniprot

MKKAVINGEQIRSISDLHQTLKKELALPEYYGENLDALWDCLAGWVEYPLVLEWRQFEQSKQLTENGAESVLQVFREAKA
EGCDITIILS