1clw

From PDBWiki

Authors	Baxa, U. Steinbacher, S. Weintraub, A. Huber, R. Seckler, R.
Citation	Mutations improving the folding of phage P22 tailspike protein affect its receptor binding activity. PubMed
Release date	2000-01-14
Exp. Method	X-RAY DIFFRACTION
Resolution	2.0 Å
Classification	Viral protein

Sequence

Chain A (554 residues): Blast Uniprot

YSIEADKKFKYSVKLSDYPTLQDAASAAVDGLLIDRDYNFYGGETVDFGGKVLTIECKAKFIGDGNLIFTKLGKGSRIAG
VFMESTTTPWVIKPWTDDNQWLTDAAAVVATLKQSKTDGYQPTVSDYVKFPGIETLLPPNAKGQNITSTLEIRECIGVEV
HRASGLMAGFLFRGCHFCKMVDANNPSGGKDGIITFENLSGDWGKGNYVIGGRTSYGSASSAQFLRNNGGFERDGGVIGF
TSYRAGESGVKTWQGTVGSTTSRNYNLQFRDSVVIYPVWDGFDLGADTDMNPELDRPGDYPITQYPLHQLPLNHLIDNLL
VRGALGVGFGMDGKGMYVSNITVEDCAGSGAYLLTHESVFTNIAIIDTNTKDFQANQIYISGACRVNGLRLIGIRSTDGQ
GLTIDAPNSTVSGITGMVDPSRINVANLAEEGLGNIRANSFGYDSAAIKLRIHKLSKTLDSGALYSHINGGAGSGSAYTQ
LTAISGSTPDAVSLKVNHKDCRGAEIPFVPDIASDDFIKDSSCFLPYWENNSTSLKALVKKPNGELVRLTLATL

User comments

Likely to be a trimer

The PISA server (http://www.ebi.ac.uk/msd-srv/prot_int/pistart.html) predicts this structure to be trimer which seems more likely than the monomeric PDB biounit.

Inconsistent mmCIF residue numbering

There is a chain break of 13.7A between the C-alpha atoms of residues 507 and 513 (395 and 396 in mmCIF residue numbering). The mmCIF numbering, which is supposed to match the SEQRES numbering, is inconsistent in this case.

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