1dg7

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1dg7

DIHYDROFOLATE REDUCTASE OF MYCOBACTERIUM TUBERCULOSIS COMPLEXED WITH NADPH AND 4-BROMO WR99210

Authors Li, R. Sirawaraporn, R. Chitnumsub, P. Sirawaraporn, W. Wooden, J. Athappilly, F. Turley, S. Hol, W.G.
Citation Three-dimensional structure of M. tuberculosis dihydrofolate reductase reveals opportunities for the design of novel tuberculosis drugs.
Release date 2000-03-09
Exp. Method X-RAY DIFFRACTION
Resolution 1.8 Å
Classification OXIDOREDUCTASE

Sequence

Chain A (159 residues): Blast Uniprot EC 1.5.1.3
MVGLIWAQATSGVIGRGGDIPWRLPEDQAHFREITMGHTIVMGRRTWDSLPAKVRPLPGRRNVVLSRQADFMASGAEVVG
SLEEALTSPETWVIGGGQVYALALPYATRCEVTEVDIGLPREAGDALAPVLDETWRGETGEWRFSRSGLRYRLYSYHRS


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