1ga9
From PDBWiki
CRYSTAL STRUCTURE OF AMPC BETA-LACTAMASE FROM E. COLI COMPLEXED WITH NON-BETA-LACTAMASE INHIBITOR (2, 3-(4-BENZENESULFONYL-THIOPHENE-2-SULFONYLAMINO)-PHENYLBORONIC ACID)
| Authors | Tondi, D. Powers, R.A. Caselli, E. Negri, M.C. Blazquez, J. Costi, M.P. Shoichet, B.K. |
| Citation | Structure-based design and in-parallel synthesis of inhibitors of AmpC beta-lactamase. PubMed |
| Release date | 2001-07-25 |
| Exp. Method | X-RAY DIFFRACTION |
| Resolution | 2.1 Å |
| Classification | HYDROLASE |
Sequence
Chain A (358 residues): Blast Uniprot EC 3.5.2.6APQQINDIVHRTITPLIEQQKIPGMAVAVIYQGKPYYFTWGYADIAKKQPVTQQTLFELGSVSKTFTGVLGGDAIARGEI KLSDPTTKYWPELTAKQWNGITLLHLATYTAGGLPLQVPDEVKSSSDLLRFYQNWQPAWAPGTQRLYANSSIGLFGALAV KPSGLSFEQAMQTRVFQPLKLNHTWINVPPAEEKNYAWGYREGKAVHVSPGALDAEAYGVKSTIEDMARWVQSNLKPLDI NEKTLQQGIQLAQSRYWQTGDMYQGLGWEMLDWPVNPDSIINGSDNKIALAARPVKAITPPTPAVRASWVHKTGATGGFG SYVAFIPEKELGIVMLANKNYPNPARVDAAWQILNALQChain B (358 residues): Blast Uniprot EC 3.5.2.6
APQQINDIVHRTITPLIEQQKIPGMAVAVIYQGKPYYFTWGYADIAKKQPVTQQTLFELGSVSKTFTGVLGGDAIARGEI KLSDPTTKYWPELTAKQWNGITLLHLATYTAGGLPLQVPDEVKSSSDLLRFYQNWQPAWAPGTQRLYANSSIGLFGALAV KPSGLSFEQAMQTRVFQPLKLNHTWINVPPAEEKNYAWGYREGKAVHVSPGALDAEAYGVKSTIEDMARWVQSNLKPLDI NEKTLQQGIQLAQSRYWQTGDMYQGLGWEMLDWPVNPDSIINGSDNKIALAARPVKAITPPTPAVRASWVHKTGATGGFG SYVAFIPEKELGIVMLANKNYPNPARVDAAWQILNALQ
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| Databases | Visualization tools | Analysis tools | Quarternary structure |
|---|---|---|---|
Categories: GA | PDB entry | X-RAY DIFFRACTION | HYDROLASE | ESCHERICHIA COLI | 2001 | EC 3.5.2.6
