1jol
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THE CRYSTAL STRUCTURE OF THE BINARY COMPLEX BETWEEN FOLINIC ACID (LEUCOVORIN) AND E. COLI DIHYDROFOLATE REDUCTASE
| Authors | Lee, H. Reyes, V.M. Kraut, J. |
| Citation | Crystal structures of Escherichia coli dihydrofolate reductase complexed with 5-formyltetrahydrofolate (folinic acid) in two space groups: evidence for enolization of pteridine O4. |
| Release date | 1996-11-08 |
| Exp. Method | X-RAY DIFFRACTION |
| Resolution | 1.96 Å |
| Classification | OXIDOREDUCTASE |
Sequence
Chain A (159 residues): Blast Uniprot EC 1.5.1.3MISLIAALAVDRVIGMENAMPWNLPADLAWFKRNTLDKPVIMGRHTWESIGRPLPGRKNIILSSQPGTDDRVTWVKSVDE AIAACGDVPEIMVIGGGRVYEQFLPKAQKLYLTHIDAEVEGDTHFPDYEPDDWESVFSEFHDADAQNSHSYCFEILERRChain B (159 residues): Blast Uniprot EC 1.5.1.3
MISLIAALAVDRVIGMENAMPWNLPADLAWFKRNTLDKPVIMGRHTWESIGRPLPGRKNIILSSQPGTDDRVTWVKSVDE AIAACGDVPEIMVIGGGRVYEQFLPKAQKLYLTHIDAEVEGDTHFPDYEPDDWESVFSEFHDADAQNSHSYCFEILERR
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| Databases | Visualization tools | Analysis tools | Quarternary structure |
|---|---|---|---|
Categories: JO | PDB entry | X-RAY DIFFRACTION | OXIDOREDUCTASE | 1996 | EC 1.5.1.3
