1js3
From PDBWiki
Crystal structure of dopa decarboxylase in complex with the inhibitor carbidopa
| Authors | Burkhard, P. Dominici, P. Borri-Voltattorni, C. Jansonius, J.N. Malashkevich, V.N. |
| Citation | Structural insight into Parkinson's disease treatment from drug-inhibited DOPA decarboxylase. |
| Release date | 2003-09-30 |
| Exp. Method | X-RAY DIFFRACTION |
| Resolution | 2.25 Å |
| Classification | LYASE |
Sequence
Chain A (486 residues): Blast Uniprot EC 4.1.1.28MNASDFRRRGKEMVDYMADYLEGIEGRQVYPDVQPGYLRPLIPATAPQEPDTFEDILQDVEKIIMPGVTHWHSPYFFAYF PTASSYPAMLADMLCGAIGCIGFSWAASPACTELETVMMDWLGKMLQLPEAFLAGEAGEGGGVIQGSASEATLVALLAAR TKVVRRLQAASPGLTQGAVLEKLVAYASDQAHSSVERAGLIGGVKLKAIPSDGKFAMRASALQEALERDKAAGLIPFFVV ATLGTTSCCSFDNLLEVGPICHEEDIWLHVDAAYAGSAFICPEFRHLLNGVEFADSFNFNPHKWLLVNFDCSAMWVKRRT DLTGAFKLDPVYLKHSHQGSGLITDYRHWQLPLGRRFRSLKMWFVFRMYGVKGLQAYIRKHVQLSHEFEAFVLQDPRFEV CAEVTLGLVCFRLKGSDGLNEALLERINSARKIHLVPCRLRGQFVLRFAICSRKVESGHVRLAWEHIRGLAAELLAAEEG KAEIKSChain B (486 residues): Blast Uniprot EC 4.1.1.28
MNASDFRRRGKEMVDYMADYLEGIEGRQVYPDVQPGYLRPLIPATAPQEPDTFEDILQDVEKIIMPGVTHWHSPYFFAYF PTASSYPAMLADMLCGAIGCIGFSWAASPACTELETVMMDWLGKMLQLPEAFLAGEAGEGGGVIQGSASEATLVALLAAR TKVVRRLQAASPGLTQGAVLEKLVAYASDQAHSSVERAGLIGGVKLKAIPSDGKFAMRASALQEALERDKAAGLIPFFVV ATLGTTSCCSFDNLLEVGPICHEEDIWLHVDAAYAGSAFICPEFRHLLNGVEFADSFNFNPHKWLLVNFDCSAMWVKRRT DLTGAFKLDPVYLKHSHQGSGLITDYRHWQLPLGRRFRSLKMWFVFRMYGVKGLQAYIRKHVQLSHEFEAFVLQDPRFEV CAEVTLGLVCFRLKGSDGLNEALLERINSARKIHLVPCRLRGQFVLRFAICSRKVESGHVRLAWEHIRGLAAELLAAEEG KAEIKS
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| Databases | Visualization tools | Analysis tools | Quarternary structure |
|---|---|---|---|
Categories: JS | PDB entry | X-RAY DIFFRACTION | LYASE | SUS SCROFA | 2003 | EC 4.1.1.28
