1kr2

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CRYSTAL STRUCTURE OF HUMAN NMN/NAMN ADENYLYL TRANSFERASE COMPLEXED WITH TIAZOFURIN ADENINE DINUCLEOTIDE (TAD)

Authors Zhou, T. Kurnasov, O. Tomchick, D.R. Binns, D.D. Grishin, N.V. Marquez, V.E. Osterman, A.L. Zhang, H.
Citation Structure of Hhuman of Nicotinamide/Nicotinic Acid Mononucleotide Adenylyltransferase.Basis for the dual substrate specificity and activation of the oncolytic agent tiazofurin. PubMed
Release date 2003-01-08
Exp. Method X-RAY DIFFRACTION
Resolution 2.3 Å
Classification TRANSFERASE

Sequence

Chain(s) A B C D E F (279 residues): Blast Uniprot EC 2.7.7.1
MENSEKTEVVLLACGSFNPITNMHLRLFELAKDYMNGTGRYTVVKGIISPVGDAYKKKGLIPAYHRVIMAELATKNSKWV
EVDTWESLQKEWKETLKVLRHHQEKLEASDCDHQQNSPTLERPGRKRKWTETQDSSQKKSLEPKTKAVPKVKLLCGADLL
ESFAVPNLWKSEDITQIVANYGLICVTRAGNDAQKFIYESDVLWKHRSNIHVVNEWIANDISSTKIRRALRRGQSIRYLV
PDLVQEYIEKHNLYSSESEDRNAGVILAPLQRNTAEAKT

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