1ly4
From PDBWiki
Analysis of quinazoline and PYRIDO[2,3D]PYRIMIDINE N9-C10 reversed bridge antifolates in complex with NADP+ and Pneumocystis carinii dihydrofolate reductase
| Authors | Cody, V. Galitsky, N. Luft, J.R. Pangborn, W. Queener, S.F. Gangjee, A. |
| Citation | Analysis of quinazoline and pyrido[2,3-d]pyrimidine N9-C10 reversed-bridge antifolates in complex with NADP+ and Pneumocystis carinii dihydrofolate reductase. |
| Release date | 2005-04-12 |
| Exp. Method | X-RAY DIFFRACTION |
| Resolution | 2.1 Å |
| Classification | OXIDOREDUCTASE |
Sequence
Chain A (206 residues): Blast Uniprot EC 1.5.1.3MNQQKSLTLIVALTTSYGIGRSNSLPWKLKKEISYFKRVTSFVPTFDSFESMNVVLMGRKTWESIPLQFRPLKGRINVVI TRNESLDLGNGIHSAKSLDHALELLYRTYGSESSVQINRIFVIGGAQLYKAAMDHPKLDRIMATIIYKDIHCDVFFPLKF RDKEWSSVWKKEKHSDLESWVGTKVPHGKINEDGFDYEFEMWTRDL
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