1pdb

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Analysis of Three Crystal Structure Determinations of a 5-Methyl-6-N-Methylanilino Pyridopyrimidine Antifolate Complex with Human Dihydrofolate Reductase

Authors	Cody, V. Luft, J.R. Pangborn, W. Gangjee, A.
Citation	Analysis of three crystal structure determinations of a 5-methyl-6-N-methylanilino pyridopyrimidine antifolate complex with human dihydrofolate reductase. PubMed
Release date	2003-12-09
Exp. Method	X-RAY DIFFRACTION
Resolution	2.2 Å
Classification	OXIDOREDUCTASE

Sequence

Chain(s) A (186 residues): Blast Uniprot EC 1.5.1.3

VGSLNCIVAVSQNMGIGKNGDLPWPPLRNEFRYFQRMTTTSSVEGKQNLVIMGKKTWFSIPEKNRPLKGRINLVLSRELK
EPPQGAHFLSRSLDDALKLTEQPELANKVDMVWIVGGSSVYKEAMNHPGHLKLFVTRIMQDFESDTFFPEIDLEKYKLLP
EYPGVLSDVQEEKGIKYKFEVYEKND