1pdb

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1pdb

Analysis of Three Crystal Structure Determinations of a 5-Methyl-6-N-Methylanilino Pyridopyrimidine Antifolate Complex with Human Dihydrofolate Reductase

Authors Cody, V. Luft, J.R. Pangborn, W. Gangjee, A.
Citation Analysis of three crystal structure determinations of a 5-methyl-6-N-methylanilino pyridopyrimidine antifolate complex with human dihydrofolate reductase. PubMed
Release date 2003-12-09
Exp. Method X-RAY DIFFRACTION
Resolution 2.2 Å
Classification OXIDOREDUCTASE

Sequence

Chain A (186 residues): Blast Uniprot EC 1.5.1.3
VGSLNCIVAVSQNMGIGKNGDLPWPPLRNEFRYFQRMTTTSSVEGKQNLVIMGKKTWFSIPEKNRPLKGRINLVLSRELK
EPPQGAHFLSRSLDDALKLTEQPELANKVDMVWIVGGSSVYKEAMNHPGHLKLFVTRIMQDFESDTFFPEIDLEKYKLLP
EYPGVLSDVQEEKGIKYKFEVYEKND


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