1q5k
From PDBWiki
crystal structure of Glycogen synthase kinase 3 in complexed with inhibitor
| Authors | Bhat, R. Xue, Y. Berg, S. Hellberg, S. Ormo, M. Nilsson, Y. Radesater, A.C. Jerning, E. Markgren, P.O. Borgegard, T. Nylof, M. Gimenez-Cassina, A. Hernandez, F. Lucas, J.J. Diaz-Nido, J. Avila, J. |
| Citation | Structural insights and biological effects of glycogen synthase kinase 3-specific inhibitor AR-A014418. PubMed |
| Release date | 2004-08-10 |
| Exp. Method | X-RAY DIFFRACTION |
| Resolution | 1.94 Å |
| Classification | TRANSFERASE |
Sequence
Chain A (414 residues): Blast Uniprot EC 2.7.11.26TTSFAESCKPVQQPSAFGSMKVSRDKDGSKVTTVVATPGQGPDRPQEVSYTDTKVIGNGSFGVVYQAKLCDSGELVAIKK VLQDKRFKNRELQIMRKLDHCNIVRLRYFFYSSGEKKDEVYLNLVLDYVPETVYRVARHYSRAKQTLPVIYVKLYMYQLF RSLAYIHSFGICHRDIKPQNLLLDPDTAVLKLCDFGSAKQLVRGEPNVSYICSRYYRAPELIFGATDYTSSIDVWSAGCV LAELLLGQPIFPGDSGVDQLVEIIKVLGTPTREQIREMNPNYTEFKFPQIKAHPWTKVFRPRTPPEAIALCSRLLEYTPT ARLTPLEACAHSFFDELRDPNVKLPNGRDTPALFNFTTQELSSNPPLATILIPPHARIQAAASTPTNATAASDANTGDRG QTNNAASASASNSTChain B (414 residues): Blast Uniprot EC 2.7.11.26
TTSFAESCKPVQQPSAFGSMKVSRDKDGSKVTTVVATPGQGPDRPQEVSYTDTKVIGNGSFGVVYQAKLCDSGELVAIKK VLQDKRFKNRELQIMRKLDHCNIVRLRYFFYSSGEKKDEVYLNLVLDYVPETVYRVARHYSRAKQTLPVIYVKLYMYQLF RSLAYIHSFGICHRDIKPQNLLLDPDTAVLKLCDFGSAKQLVRGEPNVSYICSRYYRAPELIFGATDYTSSIDVWSAGCV LAELLLGQPIFPGDSGVDQLVEIIKVLGTPTREQIREMNPNYTEFKFPQIKAHPWTKVFRPRTPPEAIALCSRLLEYTPT ARLTPLEACAHSFFDELRDPNVKLPNGRDTPALFNFTTQELSSNPPLATILIPPHARIQAAASTPTNATAASDANTGDRG QTNNAASASASNST
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| Databases | Visualization tools | Analysis tools | Quarternary structure |
|---|---|---|---|
Categories: Q5 | PDB entry | X-RAY DIFFRACTION | TRANSFERASE | HOMO SAPIENS | 2004 | EC 2.7.11.26
