1s1p
From PDBWiki
Crystal structures of prostaglandin D2 11-ketoreductase (AKR1C3) in complex with the non-steroidal anti-inflammatory drugs flufenamic acid and indomethacin
| Authors | Lovering, A.L. Ride, J.P. Bunce, C.M. Desmond, J.C. Cummings, S.M. White, S.A. |
| Citation | Crystal structures of prostaglandin D(2) 11-ketoreductase (AKR1C3) in complex with the nonsteroidal anti-inflammatory drugs flufenamic acid and indomethacin. PubMed |
| Release date | 2004-03-23 |
| Exp. Method | X-RAY DIFFRACTION |
| Resolution | 1.2 Å |
| Classification | OXIDOREDUCTASE |
Sequence
Chain A (331 residues): Blast Uniprot EC 1.-.-.-, 1.1.1.188, 1.1.1.213, 1.1.1.62, 1.3.1.20MDSKQQCVKLNDGHFMPVLGFGTYAPPEVPRSKALEVTKLAIEAGFRHIDSAHLYNNEEQVGLAIRSKIADGSVKREDIF YTSKLWSTFHRPELVRPALENSLKKAQLDYVDLYLIHSPMSLKPGEELSPTDENGKVIFDIVDLCTTWEAMEKCKDAGLA KSIGVSNFNRRQLEMILNKPGLKYKPVCNQVECHPYFNRSKLLDFCKSKDIVLVAYSALGSQRDKRWVDPNSPVLLEDPV LCALAKKHKRTPALIALRYQLQRGVVVLAKSYNEQRIRQNVQVFEFQLTAEDMKAIDGLDRNLHYFNSDSFASHPNYPYS DEYLEHHHHHH
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| Databases | Visualization tools | Analysis tools | Quarternary structure |
|---|---|---|---|
Categories: S1 | PDB entry | X-RAY DIFFRACTION | OXIDOREDUCTASE | HOMO SAPIENS | 2004 | EC 1 | EC 1.1.1.188 | EC 1.1.1.213 | EC 1.1.1.62 | EC 1.3.1.20

