1s3v
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Structure Determination of Tetrahydroquinazoline Antifolates in Complex with Human and Pneumocystis carinii Dihydrofolate Reductase: Correlations of Enzyme Selectivity and Stereochemistry
| Authors | Cody, V. Luft, J.R. Pangborn, W. Gangjee, A. Queener, S.F. |
| Citation | Structure determination of tetrahydroquinazoline antifolates in complex with human and Pneumocystis carinii dihydrofolate reductase: correlations between enzyme selectivity and stereochemistry. PubMed |
| Release date | 2004-03-30 |
| Exp. Method | X-RAY DIFFRACTION |
| Resolution | 1.8 Å |
| Classification | OXIDOREDUCTASE |
Sequence
Chain A (186 residues): Blast Uniprot EC 1.5.1.3VGSLNCIVAVSQNMGIGKNGDLPWPPLRNEFRYFQRMTTTSSVEGKQNLVIMGKKTWFSIPEKNRPLKGRINLVLSRELK EPPQGAHFLSRSLDDALKLTEQPELANKVDMVWIVGGSSVYKEAMNHPGHLKLFVTRIMQDFESDTFFPEIDLEKYKLLP EYPGVLSDVQEEKGIKYKFEVYEKND
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| Databases | Visualization tools | Analysis tools | Quarternary structure |
|---|---|---|---|
Categories: S3 | PDB entry | X-RAY DIFFRACTION | OXIDOREDUCTASE | HOMO SAPIENS | 2004 | EC 1.5.1.3
