1tg7

From PDBWiki

Authors	Rojas, A.L. Nagem, R.A.P. Neustroev, K.N. Arand, M. Adamska, M. Eneyskaya, E.V. Kulminskaya, A.A. Garratt, R.C. Golubev, A.M. Polikarpov, I.
Citation	Crystal Structures of beta-Galactosidase from Penicillium sp. and its Complex with Galactose
Release date	2005-11-01
Exp. Method	X-RAY DIFFRACTION
Resolution	1.9 Å
Classification	HYDROLASE

Sequence

Chain A (971 residues): Blast

LLQKYVTWDEHSIFVNGERLMIFSGEVHPYRLPVASLYIDIFEKVKALGFNCVSFYVDWALLEGNPGHYSAEGIFDLQPF
FDAAKEAGIYLLARPGPYINAEVSGGGFPGWLQRVDGILRTSDEAYLKATDNYASNIAATIAKAQITNGGPIILYQPENE
YSGACCGYNGFPDGSYMQYIEDHARDAGIVVPFISNDAWAAGHNAPGTGAGAVDIYGHDSYPLGFDCANPSTWPSGNLPT
YFHTSHEQQSPSTPYSLVEFQGGAFDPWGGVGFAKCAALLNHEFERVFYKNDFSFGVAFLNLYMIFGGTNWGNLGHPGGY
TSYDYGSAISESRNITREKYSELKLLGNFAKVSPGYLVANPGDLSTSTYTNTADLTVTPLLGSNSSASSFFVIRHSDYSS
QASVEYKLTVPTSAGNLTIPQLGGSLTLSGRDSKIHVTDYDVAGTNILYSTAEVFTWKKFNNEKVLVLYGGPGEHHEFAV
SGASSSSVVEGSSSGISSKKVGKALVVAWDVSTARRIVQVGSLKVFLLDRNSAYNYWVPQVPTKGTAPGYSNQETTASSI
IVKAGYLVRSAYLDGNDLHIQADFNATTPIEVVGAPSGAKNLVINGKKTQTKVDKNGIWSASVAYTAPKVQLPSLKSLKW
KSVDTLPEAKNTYDDSAWTSADHAYTNNSAHSLQTPTSLFASDYGYHTGALLFRGHFTANGKEKTFFVQTKGGTAYGHSI
WINETYVGSWAGTSINDNNNATYTLPTLQSGKNYVITVVIDNMGLDEDWTIGSEDMKNPRGIIQYSLSGQEASAISWKLT
GNLGGENYRDTVRGPLNEGGLYAERQGFHQPQPPTQKWDSSSPFTGLTKPGIRFYSTSFDLDLPSGYDIPLYFNFGNSTS
TPAAYRVQLYVNGYQYGKYVNNIGPQTSFPVPEGILNYHGTNWLALSLWAQEDNGAKLDSFELINTTPVLTSLGEVKSVN
QPKYQARKGAY

User comments

PDB format error?

This structure has a strange technical error in the entity section of the CIF file. Specifically, one water molecule is given the 'type' of 'polymer'! Water molecules should of course be annotated with a 'type' of 'water'! In fact the 1252 other water molecules in this structure are so annotated. Looking closer, we see that the formula weight of the offending molecule is 910.83 Da and not the expected 18.015 Da. This suggests that the molecule is not really water! Other strange things about the entity section makes me think that the entry needs a thorough check.

There is one other entry with such a strange 'water' molecule, 2ac1.

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