1u70

From PDBWiki

Authors	Cody, V. Luft, J.R. Pangborn, W.
Citation	Understanding the role of Leu22 variants in methotrexate resistance: comparison of wild-type and Leu22Arg variant mouse and human dihydrofolate reductase ternary crystal complexes with methotrexate and NADPH. PubMed
Release date	2005-02-01
Exp. Method	X-RAY DIFFRACTION
Resolution	2.5 Å
Classification	OXIDOREDUCTASE

Sequence

Chain A (186 residues): Blast Uniprot EC 1.5.1.3

VRPLNCIVAVSQNMGIGKNGDRPWPPLRNEFKYFQRMTTTSSVEGKQNLVIMGRKTWFSIPEKNRPLKDRINIVLSRELK
EPPRGAHFLAKSLDDALRLIEQPELASKVDMVWIVGGSSVYQEAMNQPGHLRLFVTRIMQEFESDTFFPEIDLGKYKLLP
EYPGVLSEVQEEKGIKYKFEVYEKKD

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