1ypj

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1ypj

Thrombin Inhibitor Complex

Authors Fokkens, J. Klebe, G.
Citation A simple protocol to estimate differences in protein binding affinity for enantiomers without prior resolution of racemates PubMed
Release date 2007-01-02
Exp. Method X-RAY DIFFRACTION
Resolution 1.78 Å
Classification BLOOD CLOTTING/HYDROLASE INHIBITOR

Sequence

Chain H (257 residues): Blast Uniprot EC 3.4.21.5
IVEGSDAEIGMSPWQVMLFRKSPQELLCGASLISDRWVLTAAHCLLYPPWDKNFTENDLLVRIGKHSRTRYERNIEKISM
LEKIYIHPRYNWRENLDRDIALMKLKKPVAFSDYIHPVCLPDRETAASLLQAGYKGRVTGWGNLKETWTANVGKGQPSVL
QVVNLPIVERPVCKDSTRIRITDNMFCAGYKPDEGKRGDACEGDSGGPFVMKSPFNNRWYQMGIVSWGEGCDRDGKYGFY
THVFRLKKWIQKVIDQF
Chain I (10 residues): Blast
DFEEIPEEXL
Chain L (27 residues): Blast Uniprot EC 3.4.21.5
ADCGLRPLFEKKSLEDKTERELLESYI


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