2a45

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Authors	Pechik, I. Yakovlev, S. Mosesson, M.W. Gilliland, G.L. Medved, L.
Citation	Structural basis for sequential cleavage of fibrinopeptides upon fibrin assembly.
Release date	2006-05-02
Exp. Method	X-RAY DIFFRACTION
Resolution	3.65 Å
Classification	BLOOD CLOTTING

Sequence

Chain(s) A D (36 residues): Blast Uniprot EC 3.4.21.5

TFGSGEADCGLRPLFEKKSLEDKTERELLESYIDGR

Chain(s) B E (259 residues): Blast Uniprot EC 3.4.21.5

IVEGSDAEIGMSPWQVMLFRKSPQELLCGASLISDRWVLTAAHCLLYPPWDKNFTENDLLVRIGKHSRTRYERNIEKISM
LEKIYIHPRYNWRENLDRDIALMKLKKPVAFSDYIHPVCLPDRETAASLLQAGYKGRVTGWGNLKETWTANVGKGQPSVL
QVVNLPIVERPVCKDSTRIRITDNMFCAGYKPDEGKRGDACEGDSGGPFVMKSPFNNRWYQMGIVSWGEGCDRDGKYGFY
THVFRLKKWIQKVIDQFGE

Chain(s) C F (3 residues): Blast

XPX

Chain(s) G J (57 residues): Blast Uniprot

GPRVVERHQSACKDSDWPFCSDEDWNYKCPSGCRMKGLIDEVNQDFTNRINKLKNSL

Chain(s) H K (91 residues): Blast Uniprot

GHRPLDKKREEAPSLRPAPPPISGGGYRARPAKAAATQKKVERKAPDAGGCLHADPDLGVLCPTGCQLQEALLQQERPIR
NSVDELNNNVE

Chain(s) I L (45 residues): Blast Uniprot

YVATRDNCCILDERFGSYCPTTCGIADFLSTYQTKVDKDLQSLED

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