2a4l

From PDBWiki

Authors	De Azevedo, W.F. Leclerc, S. Meijer, L. Havlicek, L. Strnad, M. Kim, S.H.
Citation	Inhibition of cyclin-dependent kinases by purine analogues: crystal structure of human cdk2 complexed with roscovitine.
Release date	2006-10-03
Exp. Method	X-RAY DIFFRACTION
Resolution	2.4 Å
Classification	TRANSFERASE

Sequence

Chain A (298 residues): Blast

MENFQKVEKIGEGTYGVVYKARNKLTGEVVALKKIRLDTETEGVPSTAIREISLLKELNHPNIVKLLDVIHTENKLYLVF
EFLHQDLKKFMDASALTGIPLPLIKSYLFQLLQGLAFCHSHRVLHRDLKPQNLLINTEGAIKLADFGLARAFGVPVRTYT
HEVVTLWYRAPEILLGCKYYSTAVDIWSLGCIFAEMVTRRALFPGDSEIDQLFRIFRTLGTPDEVVWPGVTSMPDYKPSF
PKWARQDFSKVVPPLDEDGRSLLSQMLHYDPNKRISAKAALAHPFFQDVTKPVPHLRL

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