2a4o

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2a4o

Dual modes of modification of Hepatitis A virus 3C protease by a serine derived beta-lactone: selective crytstallization and high resolution structure of the His102 adduct

Authors Yin, J. Bergmann, E.M. Cherney, M.M. Lall, M.S. Jain, R.P. Vederas, J.C. James, M.N.G.
Citation Dual Modes of Modification of Hepatitis A Virus 3C Protease by a Serine-derived beta-Lactone: Selective Crystallization and Formation of a Functional Catalytic Triad in the Active Site PubMed
Release date 2005-12-27
Exp. Method X-RAY DIFFRACTION
Resolution 1.55 Å
Classification HYDROLASE

Sequence

Chain A (219 residues): Blast Uniprot
STLEIAGLVRKNLVQFGVGEKNGSVRWVMNALGVKDDWLLVPSHAYKFEKDYEMMEFYFNRGGTYYSISAGNVVIQSLDV
GFQDVVLMKVPTIPKFRDITQHFIKKGDVPRALNRLATLVTTVNGTPMLISEGPLKMEEKATYVHKKNDGTTVDLTVDQA
WRGKGEGLPGMCGGALVSSNQSIQNAILGIHVAGGNSILVAKLVTQEMFQNIDKKIESQ


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