2a7q
From PDBWiki
Crystal structure of human dCK complexed with clofarabine and ADP
| Authors | Zhang, Y. Secrist, J.A. Ealick, S.E. |
| Citation | The structure of human deoxycytidine kinase in complex with clofarabine reveals key interactions for prodrug activation. PubMed |
| Release date | 2006-01-24 |
| Exp. Method | X-RAY DIFFRACTION |
| Resolution | 2.55 Å |
| Classification | transferase |
Sequence
Chain A (263 residues): Blast Uniprot EC 2.7.1.74GSHMATPPKRSCPSFSASSEGTRIKKISIEGNIAAGKSTFVNILKQLCEDWEVVPEPVARWCNVQSTQDEFEELTMSQKN GGNVLQMMYEKPERWSFTFQTYACLSRIRAQLASLNGKLKDAEKPVLFFERSVYSDRYIFASNLYESECMNETEWTIYQD WHDWMNNQFGQSLELDGIIYLQATPETCLHRIYLRGRNEEQGIPLEYLEKLHYKHESWLLHRTLKTNFDYLQEVPILTLD VNEDFKDKYESLVEKVKEFLSTL
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| Databases | Visualization tools | Analysis tools | Quarternary structure |
|---|---|---|---|
Categories: A7 | PDB entry | X-RAY DIFFRACTION | TRANSFERASE | HOMO SAPIENS | 2006 | EC 2.7.1.74
