2anj

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2anj

Crystal Structure of the Glur2 Ligand Binding Core (S1S2J-Y450W) Mutant in Complex With the Partial Agonist Kainic Acid at 2.1 A Resolution

Authors Holm, M.M. Naur, P. Vestergaard, B. Geballe, M.T. Gajhede, M. Kastrup, J.S. Traynelis, S.F. Egebjerg, J.
Citation A Binding Site Tyrosine Shapes Desensitization Kinetics and Agonist Potency at GluR2: a mutagenic, kinetic, and crystallographic study
Release date 2005-11-01
Exp. Method X-RAY DIFFRACTION
Resolution 2.1 Å
Classification MEMBRANE PROTEIN

Sequence

Chain A (263 residues): Blast Uniprot
GANKTVVVTTILESPYVMMKKNHEMLEGNERYEGYCVDLAAEIAKHCGFKYKLTIVGDGKWGARDADTKIWNGMVGELVY
GKADIAIAPLTITLVREEVIDFSKPFMSLGISIMIKKGTPIESAEDLSKQTEIAYGTLDSGSTKEFFRRSKIAVFDKMWT
YMRSAEPSVFVRTTAEGVARVRKSKGKYAYLLESTMNEYIEQRKPCDTMKVGGNLDSKGYGIATPKGSSLGNAVNLAVLK
LNEQGLLDKLKNKWWYDKGECGS


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