2aoe

crystal structure analysis of HIV-1 protease mutant V82A with a substrate analog CA-P2

Authors	Tie, Y. Boross, P.I. Wang, Y.F. Gaddis, L. Liu, F. Chen, X. Tozser, J. Harrison, R.W. Weber, I.T.
Citation	Molecular basis for substrate recognition and drug resistance from 1.1 to 1.6 angstroms resolution crystal structures of HIV-1 protease mutants with substrate analogs. PubMed
Release date	2006-01-17
Exp. Method	X-RAY DIFFRACTION
Resolution	1.54 Å
Classification	HYDROLASE

Sequence

Chain(s) A B (99 residues): Blast Uniprot EC 3.4.23.16

PQITLWKRPLVTIKIGGQLKEALLDTGADDTVIEEMSLPGRWKPKMIGGIGGFIKVRQYDQIIIEIAGHKAIGTVLVGPT
PANIIGRNLLTQIGATLNF

Chain(s) C (7 residues): Blast

RVXFEAX