2aoh

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Crystal structure analysis of HIV-1 Protease mutant V82A with a substrate analog P6-PR

Authors Tie, Y. Boross, P.I. Wang, Y.F. Gaddis, L. Liu, F. Chen, X. Tozser, J. Harrison, R.W. Weber, I.T.
Citation Molecular basis for substrate recognition and drug resistance from 1.1 to 1.6 angstroms resolution crystal structures of HIV-1 protease mutants with substrate analogs. PubMed
Release date 2006-01-17
Exp. Method X-RAY DIFFRACTION
Resolution 1.42 Å
Classification HYDROLASE

Sequence

Chain(s) A B (99 residues): Blast Uniprot EC 3.4.23.16
PQITLWKRPLVTIKIGGQLKEALLDTGADDTVIEEMSLPGRWKPKMIGGIGGFIKVRQYDQIIIEIAGHKAIGTVLVGPT
PANIIGRNLLTQIGATLNF
Chain(s) C (10 residues): Blast
VSFNXPQITA

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