2auh
From PDBWiki
Crystal structure of the Grb14 BPS region in complex with the insulin receptor tyrosine kinase
| Authors | Depetris, R.S. Hu, J. Gimpelevich, I. Holt, L.J. Daly, R.J. Hubbard, S.R. |
| Citation | Structural basis for inhibition of the insulin receptor by the adaptor protein grb14. PubMed |
| Release date | 2005-11-01 |
| Exp. Method | X-RAY DIFFRACTION |
| Resolution | 3.2 Å |
| Classification | TRANSFERASE/SIGNALING PROTEIN |
Sequence
Chain(s) A (306 residues): Blast Uniprot EC 2.7.1.112VFPSSVYVPDEWEVSREKITLLRELGQGSFGMVYEGNARDIIKGEAETRVAVKTVNESASLRERIEFLNEASVMKGFTCH HVVRLLGVVSKGQPTLVVMELMAHGDLKSYLRSLRPEAENNPGRPPPTLQEMIQMAAEIADGMAYLNAKKFVHRDLAARN CMVAHDFTVKIGDFGMTRDIXETDXXRKGGKGLLPVRWMAPESLKDGVFTTSSDMWSFGVVLWEITSLAEQPYQGLSNEQ VLKFVMDGGYLDQPDNCPERVTDLMRMCWQFNPNMRPTFLEIVNLLKDDLHPSFPEVSFFHSEENKChain(s) B (59 residues): Blast Uniprot
SSQSISPMRSISENSLVAMDFSGQKSRVIENPTEALSVAVEEGLAWRKKGSLRLGTHGS
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