2azt
From PDBWiki
Crystal structure of H176N mutant of human Glycine N-Methyltransferase
| Authors | Luka, Z. Pakhomova, S. Luka, Y. Newcomer, M.E. Wagner, C. |
| Citation | Destabilization of human glycine N-methyltransferase by H176N mutation. PubMed |
| Release date | 2007-10-23 |
| Exp. Method | X-RAY DIFFRACTION |
| Resolution | 2.7 Å |
| Classification | TRANSFERASE |
Sequence
Chain A (295 residues): Blast Uniprot EC 2.1.1.20MVDSVYRTRSLGVAAEGLPDQYADGEAARVWQLYIGDTRSRTAEYKAWLLGLLRQHGCQRVLDVACGTGVDSIMLVEEGF SVTSVDASDKMLKYALKERWNRRHEPAFDKWVIEEANWMTLDKDVPQSAEGGFDAVICLGNSFAHLPDCKGDQSEHRLAL KNIASMVRAGGLLVIDNRNYDHILSTGCAPPGKNIYYKSDLTKDVTTSVLIVNNKAHMVTLDYTVQVPGAGQDGSPGLSK FRLSYYPHCLASFTELLQAAFGGKCQHSVLGDFKPYKPGQTYIPCYFIHVLKRTDChain B (295 residues): Blast Uniprot EC 2.1.1.20
MVDSVYRTRSLGVAAEGLPDQYADGEAARVWQLYIGDTRSRTAEYKAWLLGLLRQHGCQRVLDVACGTGVDSIMLVEEGF SVTSVDASDKMLKYALKERWNRRHEPAFDKWVIEEANWMTLDKDVPQSAEGGFDAVICLGNSFAHLPDCKGDQSEHRLAL KNIASMVRAGGLLVIDNRNYDHILSTGCAPPGKNIYYKSDLTKDVTTSVLIVNNKAHMVTLDYTVQVPGAGQDGSPGLSK FRLSYYPHCLASFTELLQAAFGGKCQHSVLGDFKPYKPGQTYIPCYFIHVLKRTD
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