2btm
From PDBWiki
DOES THE HIS12-LYS13 PAIR PLAY A ROLE IN THE ADAPTATION OF THERMOPHILIC TIMS TO HIGH TEMPERATURES?
| Authors | Alvarez, M. Wouters, J. Maes, D. Mainfroid, V. Rentier-Delrue, F. Wyns, L. Depiereux, E. Martial, J.A. |
| Citation | Lys13 plays a crucial role in the functional adaptation of the thermophilic triose-phosphate isomerase from Bacillus stearothermophilus to high temperatures. |
| Release date | 1999-12-29 |
| Exp. Method | X-RAY DIFFRACTION |
| Resolution | 2.4 Å |
| Classification | ISOMERASE |
Sequence
Chain A (252 residues): Blast Uniprot EC 5.3.1.1RKPIIAGNWKMNGTLAEAVQFVEDVKGHVPPADEVISVVCAPFLFLDRLVQAADGTDLKIGAQTMHFADQGAYTGEVSPV MLKDLGVTYVILGHSERRQMFAETDETVNKKVLAAFTRGLIPIICCGESLEEREAGQTNAVVASQVEKALAGLTPEQVKQ AVIAYEPIWAIGTGKSSTPEDANSVCGHIRSVVSRLFGPEAAEAIRIQYGGSVKPDNIRDFLAQQQIDGALVGGASLEPA SFLQLVEAGRHEChain B (252 residues): Blast Uniprot EC 5.3.1.1
RKPIIAGNWKMNGTLAEAVQFVEDVKGHVPPADEVISVVCAPFLFLDRLVQAADGTDLKIGAQTMHFADQGAYTGEVSPV MLKDLGVTYVILGHSERRQMFAETDETVNKKVLAAFTRGLIPIICCGESLEEREAGQTNAVVASQVEKALAGLTPEQVKQ AVIAYEPIWAIGTGKSSTPEDANSVCGHIRSVVSRLFGPEAAEAIRIQYGGSVKPDNIRDFLAQQQIDGALVGGASLEPA SFLQLVEAGRHE
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