2cn0

From PDBWiki

Authors	Hoffmann-Roder, A. Schweizer, E. Egger, J. Seiler, P. Obst-Sander, U. Wagner, B. Kansy, M. Banner, D.W. Diederich, F.
Citation	Mapping the fluorophilicity of a hydrophobic pocket: synthesis and biological evaluation of tricyclic thrombin inhibitors directing fluorinated alkyl groups into the p pocket. PubMed
Release date	2007-01-03
Exp. Method	X-RAY DIFFRACTION
Resolution	1.3 Å
Classification	HYDROLASE

Sequence

Chain H (257 residues): Blast Uniprot EC 3.4.21.5

IVEGSDAEIGMSPWQVMLFRKSPQELLCGASLISDRWVLTAAHCLLYPPWDKNFTENDLLVRIGKHSRTRYERNIEKISM
LEKIYIHPRYNWRENLDRDIALMKLKKPVAFSDYIHPVCLPDRETAASLLQAGYKGRVTGWGNLKETWTANVGKGQPSVL
QVVNLPIVERPVCKDSTRIRITDNMFCAGYKPDEGKRGDACEGDSGGPFVMKSPFNNRWYQMGIVSWGEGCDRDGKYGFY
THVFRLKKWIQKVIDQF

Chain I (10 residues): Blast Uniprot

FEEIPEEYLQ

Chain L (28 residues): Blast Uniprot EC 3.4.21.5

ADCGLRPLFEKKSLEDKTERELLESYID

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