2o1o

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Cryptosporidium parvum putative polyprenyl pyrophosphate synthase (cgd4_2550) in complex with risedronate.

Authors Artz, J.D. Dunford, J.E. Arrowood, M.J. Dong, A. Chruszcz, M. Kavanagh, K.L. Minor, W. Russell, R.G. Ebetino, F.H. Oppermann, U. Hui, R.
Citation Targeting a uniquely nonspecific prenyl synthase with bisphosphonates to combat cryptosporidiosis PubMed
Release date 2006-12-12
Exp. Method X-RAY DIFFRACTION
Resolution 2.42 Å
Classification STRUCTURAL GENOMICS, UNKNOWN FUNCTION

Sequence

Chain(s) A B (368 residues): Blast Uniprot
MGSSHHHHHHSSGRENLYFQGEYDYTDFINYYDKFKVIVYNVLKKLPLNDEIRKPVIEYYLNCIDYNVKKGKHIRGKILV
LISSLSSAYSNIKRDSIYLLGWVVEAIQALILIADDIMDSGKFRRGAPCWYIVHGQSNAINDIFFLKMLSLSLIFELSSV
FGNDIVMKIQKIYNESIFFTVLGQHLDLSYFDLSKADKISERYFSMVEMKTSRYTFYMPVFFGLTLSEIQVSSAQLNLIE
AILYKLGEFYQVHNDVSDYLFNDSNADDICRFKLTWPLQKSFEIADEEMKLKISENYGKNSSLVKDCYNLLKINEHYLEY
QRNALDYLIKLVKDITDDSLQKVFIHLIHQISELITNSRSNADSNNSL

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