2o1y

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Solution structure of the anti-apoptotic protein Bcl-xL in complex with an acyl-sulfonamide-based ligand

Authors	Bruncko, M. Oost, T.K. Belli, B.A. Ding, H. Joseph, M.K. Kunzer, A. Martineau, D. McClellan, W.J. Mitten, M. Ng, S.C. Nimmer, P.M. Oltersdorf, T. Park, C.M. Petros, A.M. Shoemaker, A.R. Song, X. Wang, X. Wendt, M.D. Zhang, H. Fesik, S.W. Rosenberg, S.H. Elmore, S.W.
Citation	Studies Leading to Potent, Dual Inhibitors of Bcl-2 and Bcl-xL. PubMed
Release date	2007-02-27
Exp. Method	SOLUTION NMR
Resolution	0.0 Å
Classification	APOPTOSIS

Sequence

Chain(s) A (181 residues): Blast Uniprot

MSMAMSQSNRELVVDFLSYKLSQKGYSWSQFSDVEENRTEAPEGTESEAVKQALREAGDEFELRYRRAFSDLTSQLHITP
GTAYQSFEQVVNELFRDGVNWGRIVAFFSFGGALCVESVDKEMQVLVSRIAAWMATYLNDHLEPWIQENGGWDTFVELYG
NNAAAESRKGQERLEHHHHHH