2p33

From PDBWiki

Authors	Alam, M. Beevers, R.E. Ceska, T. Davenport, R.J. Dickson, K.M. Fortunato, M. Gowers, L. Haughan, A.F. James, L.A. Jones, M.W. Kinsella, N. Lowe, C. Meissner, J.W. Nicolas, A.L. Perry, B.G. Phillips, D.J. Pitt, W.R. Platt, A. Ratcliffe, A.J. Sharpe, A. Tait, L.J.
Citation	Synthesis and SAR of aminopyrimidines as novel c-Jun N-terminal kinase (JNK) inhibitors PubMed
Release date	2007-06-19
Exp. Method	X-RAY DIFFRACTION
Resolution	2.4 Å
Classification	TRANSFERASE

Sequence

Chain A (365 residues): Blast Uniprot EC 2.7.11.24

MGSKSKVDNQFYSVEVGDSTFTVLKRYQNLKPIGSGAQGIVCAAYDAVLDRNVAIKKLSRPFQNQTHAKRAYRELVLMKC
VNHKNIISLLNVFTPQKTLEEFQDVYLVMELMDANLCQVIQMELDHERMSYLLYQMLCGIKHLHSAGIIHRDLKPSNIVV
KSDCTLKILDFGLARTAGTSFMMTPYVVTRYYRAPEVILGMGYKENVDIWSVGCIMGEMVRHKILFPGRDYIDQWNKVIE
QLGTPCPEFMKKLQPTVRNYVENRPKYAGLTFPKLFPDSLFPADSEHNKLKASQARDLLSKMLVIDPAKRISVDDALQHP
YINVWYDPAEVEAPPPQIYDKQLDEREHTIEEWKELIYKEVMNSE

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