2p3d

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2p3d

Crystal Structure of the multi-drug resistant mutant subtype F HIV protease complexed with TL-3 inhibitor

Authors Sanches, M. Krauchenco, S. Martins, N.H. Gustchina, A. Wlodawer, A. Polikarpov, I.
Citation Structural Characterization of B and non-B Subtypes of HIV-Protease: Insights into the Natural Susceptibility to Drug Resistance Development.
Release date 2007-05-29
Exp. Method X-RAY DIFFRACTION
Resolution 2.8 Å
Classification HYDROLASE

Sequence

Chain A (99 residues): Blast
PQITLWKRPIVTIKVEGQLREALLDTGADDTVLEDINLSGKWKPKIIGGIRGFVKVKQYEDILIEICGHRAVGAVLVGPT
PANIIGRNMLTQIGCTLNF
Chain B (99 residues): Blast
PQITLWKRPIVTIKVEGQLREALLDTGADDTVLEDINLSGKWKPKIIGGIRGFVKVKQYEDILIEICGHRAVGAVLVGPT
PANIIGRNMLTQIGCTLNF


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