2p3o
From PDBWiki
Crystal Structure of Dengue Methyltransferase in Complex with 7MeGpppA and S-Adenosyl-L-homocysteine
| Authors | Egloff, M.P. Decroly, E. Malet, H. Selisko, B. Benarroch, D. Ferron, F. Canard, B. |
| Citation | Structural and functional analysis of methylation and 5'-RNA sequence requirements of short capped RNAs by the methyltransferase domain of dengue virus NS5 PubMed |
| Release date | 2007-11-20 |
| Exp. Method | X-RAY DIFFRACTION |
| Resolution | 2.756 Å |
| Classification | VIRAL PROTEIN,TRANSFERASE |
Sequence
Chain A (305 residues): Blast UniprotMRGSHHHHHHGSNIGETLGEKWKSRLNALGKSEFQIYKKSGIQEVDRTLAKEGIKRGETDHHAVSRGSAKLRWFVERNLV TPEGKVVDLGCGRGGWSYYCGGLKNVREVKGLTKGGPGHEEPIPMSTYGWNLVRLQSGVDVFFIPPERCDTLLCDIGESS PNPTVEAGRTLRVLNLVENWLSNNTQFCVKVLNPYMSSVIEKMEALQRKHGGALVRNPLSRNSTHEMYWVSNASGNIVSS VNMISRMLINRFTMRHKKATYEPDVDLGSGTRNIGIESETPNLDIIGKRIEKIKQEHETSWHYDQ
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