2p4y
From PDBWiki
Crystal structure of human PPAR-gamma-ligand binding domain complexed with an indole-based modulator
| Authors | Einstein, M. Akiyama, T.E. Castriota, G.A. Wang, C.F. McKeever, B. Mosley, R.T. Becker, J.W. Moller, D.E. Meinke, P.T. Wood, H.B. Berger, J.P. |
| Citation | The differential interactions of peroxisome proliferator-activated receptor gamma ligands with Tyr473 is a physical basis for their unique biological activities. PubMed |
| Release date | 2008-01-08 |
| Exp. Method | X-RAY DIFFRACTION |
| Resolution | 2.25 Å |
| Classification | TRANSCRIPTION |
Sequence
Chain A (277 residues): Blast UniprotGSQLNPESADLRALAKHLYDSYIKSFPLTKAKARAILTGKTTDKSPFVIYDMNSLMMGEDKIKFKHITPLQEQSKEVAIR IFQGCQFRSVEAVQEITEYAKSIPGFVNLDLNDQVTLLKYGVHEIIYTMLASLMNKDGVLISEGQGFMTREFLKSLRKPF GDFMEPKFEFAVKFNALELDDSDLAIFIAVIILSGDRPGLLNVKPIEDIQDNLLQALELQLKLNHPESSQLFAKLLQKMT DLRQIVTEHVQLLQVIKKTETDMSLHPLLQEIYKDLYChain B (277 residues): Blast Uniprot
GSQLNPESADLRALAKHLYDSYIKSFPLTKAKARAILTGKTTDKSPFVIYDMNSLMMGEDKIKFKHITPLQEQSKEVAIR IFQGCQFRSVEAVQEITEYAKSIPGFVNLDLNDQVTLLKYGVHEIIYTMLASLMNKDGVLISEGQGFMTREFLKSLRKPF GDFMEPKFEFAVKFNALELDDSDLAIFIAVIILSGDRPGLLNVKPIEDIQDNLLQALELQLKLNHPESSQLFAKLLQKMT DLRQIVTEHVQLLQVIKKTETDMSLHPLLQEIYKDLY
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Categories: P4 | PDB entry | X-RAY DIFFRACTION | TRANSCRIPTION | HOMO SAPIENS | 2008
