2q5k

Crystal structure of lopinavir bound to wild type HIV-1 protease

Authors	Reddy, G.S. Ali, A. Nalam, M.N. Anjum, S.G. Cao, H. Nathans, R.S. Schiffer, C.A. Rana, T.M.
Citation	Design and Synthesis of HIV-1 Protease Inhibitors Incorporating Oxazolidinones as P2/P2' Ligands in Pseudosymmetric Dipeptide Isosteres. PubMed
Release date	2007-09-11
Exp. Method	X-RAY DIFFRACTION
Resolution	1.95 Å
Classification	HYDROLASE

Sequence

Chain A (99 residues): Blast Uniprot

PQITLWKRPLVTIRIGGQLKEALLDTGADDTVLEEMNLPGKWKPKMIGGIGGFIKVRQYDQIPIEICGHKAIGTVLVGPT
PVNIIGRNLLTQIGCTLNF

Chain B (99 residues): Blast Uniprot

PQITLWKRPLVTIRIGGQLKEALLDTGADDTVLEEMNLPGKWKPKMIGGIGGFIKVRQYDQIPIEICGHKAIGTVLVGPT
PVNIIGRNLLTQIGCTLNF