2q5q
From PDBWiki
X-ray structure of phenylpyruvate decarboxylase in complex with 3-deaza-ThDP and 5-phenyl-2-oxo-valeric acid
| Authors | Versees, W. Spaepen, S. Wood, M.D. Leeper, F.J. Vanderleyden, J. Steyaert, J. |
| Citation | Molecular mechanism of allosteric substrate activation in a thiamine diphosphate-dependent decarboxylase. PubMed |
| Release date | 2007-10-23 |
| Exp. Method | X-RAY DIFFRACTION |
| Resolution | 1.9 Å |
| Classification | LYASE |
Sequence
Chain(s) A B (565 residues): Blast Uniprot EC 4.1.1.43MGSSHHHHHHSSGLVPRGSHMKLAEALLRALKDRGAQAMFGIPGDFALPFFKVAEETQILPLHTLSHEPAVGFAADAAAR YSSTLGVAAVTYGAGAFNMVNAVAGAYAEKSPVVVISGAPGTTEGNAGLLLHHQGRTLDTQFQVFKEITVAQARLDDPAK APAEIARVLGAARAQSRPVYLEIPRNMVNAEVEPVGDDPAWPVDRDALAACADEVLAAMRSATSPVLMVCVEVRRYGLEA KVAELAQRLGVPVVTTFMGRGLLADAPTPPLGTYIGVAGDAEITRLVEESDGLFLLGAILSDTNFAVSQRKIDLRKTIHA FDRAVTLGYHTYADIPLAGLVDALLERLPPSDRTTRGKEPHAYPTGLQADGEPIAPMDIARAVNDRVRAGQEPLLIAADM GDCLFTAMDMIDAGLMAPGYYAGMGFGVPAGIGAQCVSGGKRILTVVGDGAFQMTGWELGNCRRLGIDPIVILFNNASWE MLRTFQPESAFNDLDDWRFADMAAGMGGDGVRVRTRAELKAALDKAFATRGRFQLIEAMIPRGVLSDTLARFVQGQKRLH AAPRE
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