2r3r
From PDBWiki
Crystal Structure of Cyclin-Dependent Kinase 2 with inhibitor
| Authors | Fischmann, T.O. Hruza, A. Duca, J.S. Ramanathan, L. Mayhood, T. Windsor, W.T. Le, H.V. Guzi, T.J. Dwyer, M.P. Paruch, K. Doll, R.J. Lees, E. Parry, D. Seghezzi, W. Madison, V. |
| Citation | Structure-guided discovery of cyclin-dependent kinase inhibitors. |
| Release date | 2008-01-22 |
| Exp. Method | X-RAY DIFFRACTION |
| Resolution | 1.47 Å |
| Classification | TRANSFERASE |
Sequence
Chain(s) A (298 residues): Blast Uniprot EC 2.7.11.22MENFQKVEKIGEGTYGVVYKARNKLTGEVVALKKIRLDTETEGVPSTAIREISLLKELNHPNIVKLLDVIHTENKLYLVF EFLHQDLKKFMDASALTGIPLPLIKSYLFQLLQGLAFCHSHRVLHRDLKPQNLLINTEGAIKLADFGLARAFGVPVRTYT HEVVTLWYRAPEILLGCKYYSTAVDIWSLGCIFAEMVTRRALFPGDSEIDQLFRIFRTLGTPDEVVWPGVTSMPDYKPSF PKWARQDFSKVVPPLDEDGRSLLSQMLHYDPNKRISAKAALAHPFFQDVTKPVPHLRL
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