3a40

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Crystal structure of the human VDR ligand binding domain bound to the synthetic agonist compound 2alpha-methyl-AMCR277B(C23R)

Authors	Antony, P. Huet, T. Sato, Y. Ramalanjaona, N. Rodrigues, L.C. Moras, D. Rochel, N.
Citation	Structure-Function Relationships and Crystal Structures of the Vitamin D Receptor Bound 2alpha-Methyl-(20S,23S)- and 2alpha-Methyl-(20S,23R)-epoxymethano-1alpha,25-dihydroxyvitamin D(3) PubMed
Release date	2010-02-02
Exp. Method	X-RAY DIFFRACTION
Resolution	1.45 Å
Classification	GENE REGULATION

Sequence

Chain(s) X (263 residues): Blast Uniprot

GSHMDSLRPKLSEEQQRIIAILLDAHHKTYDPTYSDFCQFRPPVRVNDGGGSVTLELSQLSMLPHLADLVSYSIQKVIGF
AKMIPGFRDLTSEDQIVLLKSSAIEVIMLRSNESFTMDDMSWTCGNQDYKYRVSDVTKAGHSLELIEPLIKFQVGLKKLN
LHEEEHVLLMAICIVSPDRPGVQDAALIEAIQDRLSNTLQTYIRCRHPPPGSHLLYAKMIQKLADLRSLNEEHSKQYRCL
SFQPECSMKLTPLVLEVFGNEIS