3b2w

From PDBWiki

Authors	Deak, H.L. Newcomb, J.R. Nunes, J.J. Boucher, C. Cheng, A.C. DiMauro, E.F. Epstein, L.F. Gallant, P. Hodous, B.L. Huang, X. Lee, J.H. Patel, V.F. Schneider, S. Turci, S.M. Zhu, X.
Citation	N-(3-(phenylcarbamoyl)arylpyrimidine)-5-carboxamides as potent and selective inhibitors of Lck: structure, synthesis and SAR. PubMed
Release date	2008-02-19
Exp. Method	X-RAY DIFFRACTION
Resolution	2.3 Å
Classification	TRANSFERASE

Sequence

Chain A (277 residues): Blast Uniprot EC 2.7.10.2

TQKPQKPWWEDEWEVPRETLKLVERLGAGQFGEVWMGYYNGHTKVAVKSLKQGSMSPDAFLAEANLMKQLQHQRLVRLYA
VVTQEPIYIITEYMENGSLVDFLKTPSGIKLTINKLLDMAAQIAEGMAFIEERNYIHRDLRAANILVSDTLSCKIADFGL
ARLIEDNEYTAREGAKFPIKWTAPEAINYGTFTIKSDVWSFGILLTEIVTHGRIPYPGMTNPEVIQNLERGYRMVRPDNC
PEELYQLMRLCWKERPEDRPTFDYLRSVLEDFFTATE

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