3b6t

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3b6t

Crystal Structure of the GLUR2 Ligand Binding Core (S1S2J) T686A Mutant in Complex with Quisqualate at 2.1 Resolution

Authors Zhang, W. Cho, Y. Lolis, E. Howe, J.R.
Citation Structural and single-channel results indicate that the rates of ligand binding domain closing and opening directly impact AMPA receptor gating.
Release date 2008-02-05
Exp. Method X-RAY DIFFRACTION
Resolution 2.1 Å
Classification MEMBRANE PROTEIN

Sequence

Chain A (263 residues): Blast Uniprot
GANKTVVVTTILESPYVMMKKNHEMLEGNERYEGYCVDLAAEIAKHCGFKYKLTIVGDGKYGARDADTKIWNGMVGELVY
GKADIAIAPLTITLVREEVIDFSKPFMSLGISIMIKKGTPIESAEDLSKQTEIAYGTLDSGSTKEFFRRSKIAVFDKMWT
YMRSAEPSVFVRTAAEGVARVRKSKGKYAYLLESTMNEYIEQRKPCDTMKVGGNLDSKGYGIATPKGSSLGNAVNLAVLK
LNEQGLLDKLKNKWWYDKGECGS


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