3bgl

From PDBWiki

Authors	Park, W.K. Kennedy, R.M. Larsen, S.D. Miller, S. Roth, B.D. Song, Y. Steinbaugh, B.A. Sun, K. Tait, B.D. Kowala, M.C. Trivedi, B.K. Auerbach, B. Askew, V. Dillon, L. Hanselman, J.C. Lin, Z. Lu, G.H. Robertson, A. Sekerke, C.
Citation	Hepatoselectivity of statins: design and synthesis of 4-sulfamoyl pyrroles as HMG-CoA reductase inhibitors. PubMed
Release date	2008-01-29
Exp. Method	X-RAY DIFFRACTION
Resolution	2.225 Å
Classification	OXIDOREDUCTASE

Sequence

Chain(s) A B C D (441 residues): Blast Uniprot EC 1.1.1.34

HHHHHHEPRPNEECLQILGNAEKGAKFLSDAEIIQLVNAKHIPAYKLETLIETHERGVSIRRQLLSKKLSEPSSLQYLPY
RDYNYSLVMGACCENVIGYMPIPVGVAGPLCLDEKEFQVPMATTEGCLVASTNRGCRAIGLGGGASSRVLADGMTRGPVV
RLPRACDSAEVKAWLETSEGFAVIKEAFDSTSRFARLQKLHTSIAGRNLYIRFQSRSGDAMGMNMISKGTEKALSKLHEY
FPEMQILAVSGNYCTDKKPAAINWIEGRGKSVVCEAVIPAKVVREVLKTTTEAMIEVNINKNLVGSAMAGSIGGYNAHAA
NIVTAIYIACGQDAAQNVGSSNCITLMEASGPTNEDLYISCTMPSIEIGTVGGGTNLLPQQACLQMLGVQGACKDNPGEN
ARQLARIVCGTVMAGELSLMAALAAGHLVKSHMIHNRSKIN

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