3cs9

From PDBWiki

Authors	Weisberg, E. Manley, P.W. Breitenstein, W. Brueggen, J. Cowan-Jacob, S.W. Ray, A. Huntly, B. Fabbro, D. Fendrich, G. Hall-Meyers, E. Kung, A.L. Mestan, J. Daley, G.Q. Callahan, L. Catley, L. Cavazza, C. Azam, M. Neuberg, D. Wright, R.D. Gilliland, D.G. Griffin, J.D.
Citation	Characterization of AMN107, a selective inhibitor of native and mutant Bcr-Abl
Release date	2008-04-22
Exp. Method	X-RAY DIFFRACTION
Resolution	2.21 Å
Classification	TRANSFERASE

Sequence

Chain(s) A B C D (277 residues): Blast Uniprot EC 2.7.10.2

GAMDPSPNYDKWEMERTDITMKHKLGGGQYGEVYEGVWKKYSLTVAVKTLKEDTMEVEEFLKEAAVMKEIKHPNLVQLLG
VCTREPPFYIITEFMTYGNLLDYLRECNRQEVNAVVLLYMATQISSAMEYLEKKNFIHRDLAARNCLVGENHLVKVADFG
LSRLMTGDTYTAHAGAKFPIKWTAPESLAYNKFSIKSDVWAFGVLLWEIATYGMSPYPGIDLSQVYELLEKDYRMERPEG
CPEKVYELMRACWQWNPSDRPSFAEIHQAFETMFQES

User comments

• add comment

Links