4cpa

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Authors	Rees, D.C. Lipscomb, W.N.
Citation	Refined crystal structure of the potato inhibitor complex of carboxypeptidase A at 2.5 A resolution.
Release date	2003-04-01
Exp. Method	X-RAY DIFFRACTION
Resolution	2.5 Å
Classification	HYDROLASE (C-TERMINAL PEPTIDASE)

Sequence

Chain A (307 residues): Blast Uniprot EC 3.4.17.1

ARSTNTFNYATYHTLDEIYDFMDLLVAQHPELVSKLQIGRSYEGRPIYVLKFSTGGSNRPAIWIDLGIHSREWITQATGV
WFAKKFTENYGQNPSFTAILDSMDIFLEIVTNPNGFAFTHSENRLWRKTRSVTSSSLCVGVDANRNWDAGFGKAGASSSP
CSETYHGKYANSEVEVKSIVDFVKNHGNFKAFLSIHSYSQLLLYPYGYTTQSIPDKTELNQVAKSAVAALKSLYGTSYKY
GSIITTIYQASGGSIDWSYNQGIKYSFTFELRDTGRYGFLLPASQIIPTAQETWLGVLTIMEHTVNN

Chain B (307 residues): Blast Uniprot EC 3.4.17.1

ARSTNTFNYATYHTLDEIYDFMDLLVAQHPELVSKLQIGRSYEGRPIYVLKFSTGGSNRPAIWIDLGIHSREWITQATGV
WFAKKFTENYGQNPSFTAILDSMDIFLEIVTNPNGFAFTHSENRLWRKTRSVTSSSLCVGVDANRNWDAGFGKAGASSSP
CSETYHGKYANSEVEVKSIVDFVKNHGNFKAFLSIHSYSQLLLYPYGYTTQSIPDKTELNQVAKSAVAALKSLYGTSYKY
GSIITTIYQASGGSIDWSYNQGIKYSFTFELRDTGRYGFLLPASQIIPTAQETWLGVLTIMEHTVNN

Chain I (38 residues): Blast Uniprot

XXHADPICNKPCKTHDDCSGAWFCQACWNSARTCGPYV

Chain J (38 residues): Blast Uniprot

XXHADPICNKPCKTHDDCSGAWFCQACWNSARTCGPYV

User comments

Number of chains changed after remediation

Source: [1]

Before remediation, PDB file 4CPA had three chains:

Protein polymer chain with no identifier, 307 residues
Protein polymer chain I, 38 residues
Protein monomer "chain" G, a single GLY residue

After remediation, 4CPA has 6 chains:

A, B = two copies of the chain formerly lacking an identifier
I, J = two copies of the former chain I
G, H = two copies of the single-residue GLY "chain"

The reason is that the ASU was not deposited originally and the wwPDB remediation generated the complete ASU (same for all single crystal X-Ray non-virial particule entries) which required new chain generation and assignments.

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