pdbwiki

Outer membrane compositions enhance the rate of extracellular electron transport via cell-surface

Moss PPR-SMR protein PpPPR_64 influences the expression of a psaA-psaB-rps14 gene cluster and processing of the 23S-4.5S rRNA precursor in chloroplasts

Moss PPR-SMR protein PpPPR_64 is a pTAC2 homolog but is functionally distinct from pTAC2. PpPPR_64 is required for psaA gene expression and its function may have evolved in mosses. The pentatricopeptide repeat (PPR) proteins are key regulatory factors responsible for the control of plant organellar gene expression. A small subset of PPR proteins possess a C-terminal small MutS-related (SMR) domain and have diverse roles in plant organellar biogenesis. However, the function of PPR-SMR proteins is not fully understood.

Here, we report the function of PPR-SMR protein PpPPR_64 in the moss Physcomitrium patens. Phylogenetic analysis indicated that PpPPR_64 belongs to the same clade as the Arabidopsis PPR-SMR protein pTAC2. PpPPR_64 knockout (KO) mutants grew autotrophically but with reduced protonemata growth and the poor formation of photosystems’ antenna complexes.

Quantitative reverse transcription-polymerase chain reaction and RNA gel blot hybridization analyses revealed a significant reduction in transcript levels of the psaA-psaB-rps14 gene cluster but no alteration to transcript levels of most photosynthesis- and non-photosynthesis-related genes.

In addition, RNA processing of 23S-4.5S rRNA precursor was impaired in the PpPPR_64 KO mutants. This suggests that PpPPR_64 is specifically involved in the expression level of the psaA-psaB-rps14 gene and in processing of the 23S-4.5S rRNA precursor. Our results indicate that PpPPR_64 is functionally distinct from pTAC2 and is a novel PPR-SMR protein required for proper chloroplast biogenesis in P. patens.

Outer membrane compositions enhance the rate of extracellular electron transport via cell-surface MtrC protein in Shewanella oneidensis MR-1

While cell membrane composition is critical for the function of membrane proteins, membrane modification has not been used to control the rate of extracellular electron transfer (EET) via the outer membrane protein complexes. Here, the rate of electron flow via the cell-surface redox protein, MtrC, was highly enhanced upon change in the outer membrane composition in Shewanella oneidensis MR-1.
The MR-1 strain was pre-cultured at 4 °C and 30 °C to initiate differentiation of membrane composition. The whole-cell difference electrochemical assay of wild-type and mutant strains lacking MtrC suggested that the rate of EET via MtrC increased approximately 18 times at 4 °C than 30 °C.
Circular dichroism spectroscopy showed that the molar exciton coupling coefficient for inter-heme interaction in MtrC increased in MR-1 at 4 °C than 30 °C. Results suggest that membrane modification may be a novel strategy for improving the efficiency of EET-based technologies.

Leucine-rich alpha-2 glycoprotein (LRG): A novel acute phase protein expressed in stage 3 grade C periodontitis before and after periodontal therapy

 

Background: Leucine-rich alpha-2 glycoprotein (LRG) is a novel acute phase protein involved in inflammation-associated diseases and that considered to be induced by multiple proinflammatory cytokines.
This study aimed to investigate gingival crevicular fluid (GCF) and serum levels of LRG, interleukin (IL)-6 and tumor necrosis factor (TNF)-α in patients with stage 3 periodontitis before and after non-surgical periodontal treatment.
Methods: Twenty-five stage 3 periodontitis and twenty-five periodontally healthy individuals were enrolled in the study. Clinical periodontal measurements were recorded; periodontitis patients received non-surgical periodontal treatment, and GCF and serum samples were obtained at baseline and at 6 weeks after treatment. LRG, IL-6 and TNF-α were determined by ELISA.
Results: GCF and serum LRG, IL-6 and TNF-α were significantly higher in periodontitis group than healthy controls (P < 0.001). A significant decrease in GCF and serum LRG, IL-6 and TNF-α was detected after periodontal treatment compared to baseline values of periodontitis patients (P < 0.001).
Conclusion: Our findings revealed that LRG expression was increased in stage 3 periodontitis both locally and systemically, and non-surgical periodontal therapy was effective in reducing LRG levels in GCF and serum of these patients. This article is protected by copyright. All rights reserved.

Aqueous Two-Phase-Assisted Precipitation of Proteins: A Platform for Isolation of Process-Related Impurities from Therapeutic Proteins

Aqueous two-phase systems (ATPS) have been widely and successfully used in the purification of various biological macromolecules such as proteins, nucleic acids, antibiotics, and cell components.
Interfacial precipitation of the product often results in lower recovery and selectivity of ATPS. Efficient resolubilization of the interfacial precipitate offers a way to improve the recovery as well as selectivity of ATPS systems.
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Tyrosyl DNA Phosphodiesterase 1 (TDP1) Antibody

20-abx131559
  • EUR 439.00
  • EUR 133.00
  • EUR 1233.00
  • EUR 592.00
  • EUR 328.00
  • 100 ug
  • 10 ug
  • 1 mg
  • 200 ug
  • 50 ug

Tyrosyl-Dna Phosphodiesterase 1 (TDP1) Antibody

20-abx116391
  • EUR 732.00
  • EUR 398.00
  • 150 ul
  • 50 ul

Tyrosyl-DNA Phosphodiesterase 1 (TDP1) Antibody

20-abx137321
  • EUR 704.00
  • EUR 328.00
  • EUR 230.00
  • 100 ug
  • 20 ug
  • 5 ug

Tyrosyl-DNA Phosphodiesterase 1 (TDP1) Antibody

20-abx007160
  • EUR 411.00
  • EUR 592.00
  • EUR 182.00
  • EUR 314.00
  • 100 ul
  • 200 ul
  • 20 ul
  • 50 ul

Tyrosyl-DNA Phosphodiesterase 1 (TDP1) Antibody

20-abx003676
  • EUR 411.00
  • EUR 592.00
  • EUR 182.00
  • EUR 314.00
  • 100 ul
  • 200 ul
  • 20 ul
  • 50 ul

Tyrosyl-DNA Phosphodiesterase 1 (TDP1) Antibody

abx029686-400ul 400 ul
EUR 523

Tyrosyl-DNA Phosphodiesterase 1 (TDP1) Antibody

abx029686-80l 80 µl
EUR 286

Tyrosyl-DNA Phosphodiesterase 1 (TDP1) Antibody

abx433352-200ul 200 ul
EUR 384

Tyrosyl-DNA Phosphodiesterase 1 (TDP1) Antibody

20-abx320393
  • EUR 300.00
  • EUR 244.00
  • 100 ul
  • 50 ul

Tyrosyl-DNA Phosphodiesterase 1 (TDP1) Antibody

20-abx322676
  • EUR 300.00
  • EUR 244.00
  • 100 ul
  • 50 ul

Tyrosyl-DNA Phosphodiesterase 1 (TDP1) Antibody

abx238572-100ug 100 ug
EUR 509

Recombinant Tyrosyl DNA Phosphodiesterase 1 (TDP1)

4-RPC785Mu01
  • EUR 395.68
  • EUR 209.00
  • EUR 1208.80
  • EUR 469.60
  • EUR 839.20
  • EUR 328.00
  • EUR 2872.00
  • 100 ug
  • 10ug
  • 1 mg
  • 200 ug
  • 500 ug
  • 50ug
  • 5 mg
Description: Recombinant Mouse Tyrosyl DNA Phosphodiesterase 1 expressed in: E.coli

Recombinant Tyrosyl DNA Phosphodiesterase 1 (TDP1)

4-RPC785Ra01
  • EUR 404.64
  • EUR 211.00
  • EUR 1242.40
  • EUR 480.80
  • EUR 861.60
  • EUR 334.00
  • EUR 2956.00
  • 100 ug
  • 10ug
  • 1 mg
  • 200 ug
  • 500 ug
  • 50ug
  • 5 mg
Description: Recombinant Rat Tyrosyl DNA Phosphodiesterase 1 expressed in: E.coli

TDP2 Tyrosyl-DNA Phosphodiesterase 2 Human Recombinant Protein

PROTO95551 Regular: 10ug
EUR 317
Description: TDP2 Human Recombinant produced in E.coli is a single, non-glycosylated polypeptide chain containing 385 amino acids (1-362) and having a molecular mass of 43.3kDa. ;TDP2 is fused to a 23 amino acid His-tag at N-terminus & purified by proprietary chromatographic techniques.

Mouse Tyrosyl- DNA phosphodiesterase 2, Tdp2 ELISA KIT

ELI-51300m 96 Tests
EUR 865

Human Tyrosyl- DNA phosphodiesterase 2, TDP2 ELISA KIT

ELI-16782h 96 Tests
EUR 824

Bovine Tyrosyl- DNA phosphodiesterase 2, TDP2 ELISA KIT

ELI-17055b 96 Tests
EUR 928

Human Tyrosyl-DNA Phosphodiesterase 1 (TDP1) Antibody

31298-05111 150 ug
EUR 261

Mouse Tyrosyl DNA Phosphodiesterase 1 (TDP1) Protein

20-abx650176
  • EUR 565.00
  • EUR 258.00
  • EUR 1636.00
  • EUR 662.00
  • EUR 411.00
  • 100 ug
  • 10 ug
  • 1 mg
  • 200 ug
  • 50 ug

Rat Tyrosyl-DNA Phosphodiesterase 1 (TDP1) Protein

20-abx650870
  • EUR 578.00
  • EUR 258.00
  • EUR 1678.00
  • EUR 676.00
  • EUR 425.00
  • 100 ug
  • 10 ug
  • 1 mg
  • 200 ug
  • 50 ug

Human Tyrosyl DNA Phosphodiesterase 1 (TDP1) ELISA Kit

20-abx585197
  • EUR 7378.00
  • EUR 3933.00
  • EUR 911.00
  • 10 × 96 tests
  • 5 × 96 tests
  • 96 tests

TDP1 Tyrosyl-DNA Phosphodiesterase 1 Human Recombinant Protein

PROTQ9NUW8 Regular: 20ug
EUR 317
Description: TDP1 Human Recombinant produced in E.coli is a single, non-glycosylated polypeptide chain containing 318 amino acids (1-298) and having a molecular mass of 35.8kDa. TDP1 is fused to a 20 amino acid His-tag at N-terminus & purified by proprietary chromatographic techniques.

Human Tyrosyl-DNA Phosphodiesterase 1(TDP1)ELISA Kit

CSB-E17810h-24T 1 plate of 24 wells
EUR 165
Description: Quantitativesandwich ELISA kit for measuring Human Tyrosyl-DNA Phosphodiesterase 1 (TDP1) in samples from serum, plasma, tissue homogenates, cell lysates. A new trial version of the kit, which allows you to test the kit in your application at a reasonable price.

Human Tyrosyl-DNA Phosphodiesterase 1(TDP1)ELISA Kit

1-CSB-E17810h
  • EUR 804.00
  • EUR 5099.00
  • EUR 2704.00
  • 1 plate of 96 wells
  • 10 plates of 96 wells each
  • 5 plates of 96 wells each
Description: Quantitativesandwich ELISA kit for measuring Human Tyrosyl-DNA Phosphodiesterase 1(TDP1) in samples from serum, plasma, tissue homogenates, cell lysates. Now available in a cost efficient pack of 5 plates of 96 wells each, conveniently packed along with the other reagents in 5 separate kits.

Tyrosyl DNA Phosphodiesterase 1 (TDP1) Polyclonal Antibody (Mouse)

4-PAC785Mu01
  • EUR 251.00
  • EUR 2576.00
  • EUR 640.00
  • EUR 316.00
  • EUR 215.00
  • 100ul
  • 10ml
  • 1ml
  • 200ul
  • 20ul
Description: A Rabbit polyclonal antibody against Mouse Tyrosyl DNA Phosphodiesterase 1 (TDP1)

Human Tyrosyl DNA Phosphodiesterase 1 (TDP1) ELISA Kit

SEC785Hu-10x96wellstestplate 10x96-wells test plate
EUR 4731.5
Description: This is Double-antibody Sandwich Enzyme-linked immunosorbent assay for detection of Human Tyrosyl DNA Phosphodiesterase 1 (TDP1) in serum, plasma, tissue homogenates, cell lysates, cell culture supernates and other biological fluids.

Human Tyrosyl DNA Phosphodiesterase 1 (TDP1) ELISA Kit

SEC785Hu-1x48wellstestplate 1x48-wells test plate
EUR 477.3
Description: This is Double-antibody Sandwich Enzyme-linked immunosorbent assay for detection of Human Tyrosyl DNA Phosphodiesterase 1 (TDP1) in serum, plasma, tissue homogenates, cell lysates, cell culture supernates and other biological fluids.

Human Tyrosyl DNA Phosphodiesterase 1 (TDP1) ELISA Kit

SEC785Hu-1x96wellstestplate 1x96-wells test plate
EUR 639
Description: This is Double-antibody Sandwich Enzyme-linked immunosorbent assay for detection of Human Tyrosyl DNA Phosphodiesterase 1 (TDP1) in serum, plasma, tissue homogenates, cell lysates, cell culture supernates and other biological fluids.

Human Tyrosyl DNA Phosphodiesterase 1 (TDP1) ELISA Kit

SEC785Hu-5x96wellstestplate 5x96-wells test plate
EUR 2575.5
Description: This is Double-antibody Sandwich Enzyme-linked immunosorbent assay for detection of Human Tyrosyl DNA Phosphodiesterase 1 (TDP1) in serum, plasma, tissue homogenates, cell lysates, cell culture supernates and other biological fluids.

Human Tyrosyl DNA Phosphodiesterase 1 (TDP1) ELISA Kit

4-SEC785Hu
  • EUR 4782.00
  • EUR 2526.00
  • EUR 640.00
  • 10 plates of 96 wells
  • 5 plates of 96 wells
  • 1 plate of 96 wells
Description: Enzyme-linked immunosorbent assay based on the Double-antibody Sandwich method for detection of Human Tyrosyl DNA Phosphodiesterase 1 (TDP1) in samples from serum, plasma, tissue homogenates, cell lysates, cell culture supernates and other biological fluids with no significant corss-reactivity with analogues from other species.

Human Tyrosyl- DNA phosphodiesterase 1, TDP1 ELISA KIT

ELI-39932h 96 Tests
EUR 824

Mouse Tyrosyl- DNA phosphodiesterase 1, Tdp1 ELISA KIT

ELI-44743m 96 Tests
EUR 865

Human Tyrosyl-DNA Phosphodiesterase 1 (TDP1) Antibody (Biotin Conjugate)

31298-05121 150 ug
EUR 369

Tyrosyl DNA Phosphodiesterase 1 (TDP1) Polyclonal Antibody (Mouse), APC

4-PAC785Mu01-APC
  • EUR 351.00
  • EUR 3365.00
  • EUR 935.00
  • EUR 449.00
  • EUR 222.00
  • 100ul
  • 10ml
  • 1ml
  • 200ul
  • 20ul
Description: A Rabbit polyclonal antibody against Mouse Tyrosyl DNA Phosphodiesterase 1 (TDP1). This antibody is labeled with APC.

Tyrosyl DNA Phosphodiesterase 1 (TDP1) Polyclonal Antibody (Mouse), Biotinylated

4-PAC785Mu01-Biotin
  • EUR 316.00
  • EUR 2526.00
  • EUR 744.00
  • EUR 387.00
  • EUR 221.00
  • 100ul
  • 10ml
  • 1ml
  • 200ul
  • 20ul
Description: A Rabbit polyclonal antibody against Mouse Tyrosyl DNA Phosphodiesterase 1 (TDP1). This antibody is labeled with Biotin.

Tyrosyl DNA Phosphodiesterase 1 (TDP1) Polyclonal Antibody (Mouse), Cy3

4-PAC785Mu01-Cy3
  • EUR 427.00
  • EUR 4445.00
  • EUR 1205.00
  • EUR 557.00
  • EUR 254.00
  • 100ul
  • 10ml
  • 1ml
  • 200ul
  • 20ul
Description: A Rabbit polyclonal antibody against Mouse Tyrosyl DNA Phosphodiesterase 1 (TDP1). This antibody is labeled with Cy3.

Tyrosyl DNA Phosphodiesterase 1 (TDP1) Polyclonal Antibody (Mouse), FITC

4-PAC785Mu01-FITC
  • EUR 301.00
  • EUR 2712.00
  • EUR 768.00
  • EUR 379.00
  • EUR 197.00
  • 100ul
  • 10ml
  • 1ml
  • 200ul
  • 20ul
Description: A Rabbit polyclonal antibody against Mouse Tyrosyl DNA Phosphodiesterase 1 (TDP1). This antibody is labeled with FITC.

Tyrosyl DNA Phosphodiesterase 1 (TDP1) Polyclonal Antibody (Mouse), HRP

4-PAC785Mu01-HRP
  • EUR 321.00
  • EUR 2933.00
  • EUR 827.00
  • EUR 405.00
  • EUR 209.00
  • 100ul
  • 10ml
  • 1ml
  • 200ul
  • 20ul
Description: A Rabbit polyclonal antibody against Mouse Tyrosyl DNA Phosphodiesterase 1 (TDP1). This antibody is labeled with HRP.

Tyrosyl DNA Phosphodiesterase 1 (TDP1) Polyclonal Antibody (Mouse), PE

4-PAC785Mu01-PE
  • EUR 301.00
  • EUR 2712.00
  • EUR 768.00
  • EUR 379.00
  • EUR 197.00
  • 100ul
  • 10ml
  • 1ml
  • 200ul
  • 20ul
Description: A Rabbit polyclonal antibody against Mouse Tyrosyl DNA Phosphodiesterase 1 (TDP1). This antibody is labeled with PE.

TDP1 Human, Tyrosyl-DNA Phosphodiesterase 1 Human Recombinant Protein, Sf9

PROTQ9NUW8-1 Regular: 5ug
EUR 317
Description: TDP1 Human Recombinant produced in Sf9 Baculovirus cells is a single, glycosylated polypeptide chain containing 617 amino acids (1-608) and having a molecular mass of 69.5kDa (Molecular size on SDS-PAGE will appear at approximately 50-70kDa). TDP1 is fused to 9 amino acid His-Tag at C-terminus and purified by proprietary chromatographic techniques. 

Human Tyrosyl-DNA Phosphodiesterase 1 (TDP1) AssayLite Antibody (FITC Conjugate)

31298-05141 150 ug
EUR 428

Human Tyrosyl-DNA Phosphodiesterase 1 (TDP1) AssayLite Antibody (RPE Conjugate)

31298-05151 150 ug
EUR 428

Human Tyrosyl-DNA Phosphodiesterase 1 (TDP1) AssayLite Antibody (APC Conjugate)

31298-05161 150 ug
EUR 428

Human Tyrosyl-DNA Phosphodiesterase 1 (TDP1) AssayLite Antibody (PerCP Conjugate)

31298-05171 150 ug
EUR 471

Tyrosyl DNA Phosphodiesterase 1 (TDP1) Polyclonal Antibody (Mouse), APC-Cy7

4-PAC785Mu01-APC-Cy7
  • EUR 583.00
  • EUR 6610.00
  • EUR 1750.00
  • EUR 778.00
  • EUR 324.00
  • 100ul
  • 10ml
  • 1ml
  • 200ul
  • 20ul
Description: A Rabbit polyclonal antibody against Mouse Tyrosyl DNA Phosphodiesterase 1 (TDP1). This antibody is labeled with APC-Cy7.

100 BP DNA LADDER, 500UL PER KIT

M-DNA-100BP 1/pk
EUR 73
Description: Bioscience Mol Bio; DNA Ladder

1 KB DNA LADDER, 500UL PER KIT

M-DNA-1KB 1/pk
EUR 70
Description: Bioscience Mol Bio; DNA Ladder

Kinetoplast DNA (catenated)

TG2013-2 50 ug
EUR 380

Tyrosyl-tRNA synthetase 2 (Recombinant)

20-abx073969
  • EUR 1609.00
  • EUR 328.00
  • EUR 230.00
  • 100 ug
  • 10 ug
  • 2 µg

Supercoiled pHOT-1 DNA

TG2030-2 50 ug
EUR 324

Relaxed pHOT-1 DNA

TG2035-2 50 ug
EUR 347

D-Tyrosyl-tRNA Deacylase 2 (Recombinant)

20-abx073420
  • EUR 3418.00
  • EUR 328.00
  • EUR 230.00
  • 1 mg
  • 20 ug
  • 5 ug

500-10000bp DNA Marker, Original Form

M101O-2 5x100loading, 500prep
EUR 219.65

100-1500bp DNA Marker, Original Form

M102O-2 5x100loading, 500prep
EUR 215.3

100-1500bp DNA Marker, Original Form

M107O-2 5x100loading, 500prep
EUR 219.65

Anti-DNA Polymerase lambda/POLL Antibody

A00959-2 100ug/vial
EUR 294

pRYG DNA (topo II target site)

TG2023-2 20 ug
EUR 302

Tyrosyl-tRNA Synthetase 2, Mitochondrial (YARS2) Antibody

20-abx116394
  • EUR 732.00
  • EUR 398.00
  • 150 ul
  • 50 ul

500-10000bp DNA Marker, Ready-to-use

M101R-2 5x100loading, 500prep
EUR 219.65

100-1500bp DNA Marker, Ready-to-use

M102R-2 5x100loading, 500prep
EUR 215.3

Lambda DNA/HindIII Marker, Ready-to-use

M104R-2 5x100loading, 500prep
EUR 124.82

Lambda DNA/HindIII Plus, Ready-to-use

M105R-2 5x100loading, 500prep
EUR 115.25

100-1500bp DNA Marker, Ready-to-use

M107R-2 5x100loading, 500prep
EUR 219.65

Topoisomerase I Assay Kit (62.5ug SC DNA)

TG1015-2 250 assays
EUR 414

Tyrosyl-tRNA synthetase (Recombinant)

20-abx073710
  • EUR 328.00
  • EUR 6397.00
  • EUR 230.00
  • 10 ug
  • 1 mg
  • 2 µg

Anti-DNA-topoisomerase II α Monoclonal Antibody (1C5)

M00953-2 100ug
EUR 420
Description: Mouse Monoclonal DNA-topoisomerase II α Antibody (1C5). Validated in Flow Cytometry, IP, IF, IHC, WB and tested in Human.

Topoisomerase II Drug Screening Kit (62.5ug SC DNA)

TG1009-2 250 assays
EUR 470

Topoisomerase I Drug Screening Kit (62.5ug SC DNA)

TG1018-2 250 assays
EUR 448

YARS2 Tyrosyl-tRNA Synthetase 2 Human Recombinant Protein

PROTQ9Y2Z4 Regular: 10ug
EUR 317
Description: YARS2 Human Recombinant produced in E.Coli is a single, non-glycosylated polypeptide chain containing 482 amino acids (17-477 a.a.) and having a molecular mass of 53.7kDa.;YARS2 is fused to a 21 amino acid His-tag at N-terminus & purified by proprietary chromatographic techniques.

Sphingomyelin Phosphodiesterase 2 (SMPD2) Antibody

abx122431-100ug 100 ug
EUR 391

Sphingomyelin Phosphodiesterase 2 (SMPD2) Antibody

abx117048-100ug 100 ug
EUR 467

Sphingomyelin Phosphodiesterase 2 (SMPD2) Antibody

20-abx001080
  • EUR 411.00
  • EUR 592.00
  • EUR 182.00
  • EUR 314.00
  • 100 ul
  • 200 ul
  • 20 ul
  • 50 ul

Sphingomyelin phosphodiesterase 2 (SMPD2) Antibody

20-abx334232
  • EUR 411.00
  • EUR 1845.00
  • EUR 599.00
  • EUR 182.00
  • EUR 300.00
  • 100 ug
  • 1 mg
  • 200 ug
  • 20 ug
  • 50 ug

Genomic DNA from hypertension: Artery, from a single donor

D1236013Hd-2 50 ug
EUR 446
Description: Can be used for various studies in the realm of gene expression, both normal and pathological. It is an excellent control and suitable for educational purposes.

Genomic DNA from hypertension: Vein, from a single donor

D1236020Hd-2 50 ug
EUR 446
Description: Can be used for various studies in the realm of gene expression, both normal and pathological. It is an excellent control and suitable for educational purposes.

Genomic DNA from hypertension: Heart, from a single donor

D1236122Hd-2 50 ug
EUR 446
Description: Can be used for various studies in the realm of gene expression, both normal and pathological. It is an excellent control and suitable for educational purposes.

Genomic DNA from hypertension: Kidney, from a single donor

D1236142Hd-2 50 ug
EUR 446
Description: Can be used for various studies in the realm of gene expression, both normal and pathological. It is an excellent control and suitable for educational purposes.

Genomic DNA from Bronchitis: Lung, from a single donor

D1236152Ld-2 50 ug
EUR 446
Description: Can be used for various studies in the realm of gene expression, both normal and pathological. It is an excellent control and suitable for educational purposes.

E. coli Topoisomerase IV Drug Screening Kit (62.5ug SC DNA)

TG1007-2 250 assays
EUR 448

Genomic DNA from hypertension: Interventricular Septum, from a single donor

D1236130Hd-2 50 ug
EUR 446
Description: Can be used for various studies in the realm of gene expression, both normal and pathological. It is an excellent control and suitable for educational purposes.

Tyrosyl tRNA Synthetase (YARS) Antibody

20-abx128983
  • EUR 425.00
  • EUR 133.00
  • EUR 1205.00
  • EUR 578.00
  • EUR 328.00
  • 100 ug
  • 10 ug
  • 1 mg
  • 200 ug
  • 50 ug

Tyrosyl tRNA Synthetase (YARS) Antibody

abx122273-100ug 100 ug
EUR 391

Tyrosyl tRNA Synthetase (YARS) Antibody

20-abx005209
  • EUR 411.00
  • EUR 592.00
  • EUR 182.00
  • EUR 314.00
  • 100 ul
  • 200 ul
  • 20 ul
  • 50 ul

Tyrosyl tRNA Synthetase (YARS) Antibody

abx033489-400ul 400 ul
EUR 523

Tyrosyl tRNA Synthetase (YARS) Antibody

abx033489-80l 80 µl
EUR 286

Tyrosyl tRNA Synthetase (YARS) Antibody

abx033490-400ul 400 ul
EUR 523

Tyrosyl tRNA Synthetase (YARS) Antibody

abx033490-80l 80 µl
EUR 286

Recombinant Human Tyrosyl-tRNA Synthetase

7-03811 2µg Ask for price

Recombinant Human Tyrosyl-tRNA Synthetase

7-03812 10µg Ask for price

Recombinant Human Tyrosyl-tRNA Synthetase

7-03813 1mg Ask for price

Tyrosyl-tRNA Synthetase (YARS) Antibody

20-abx142315
  • EUR 370.00
  • EUR 606.00
  • EUR 314.00
  • 100 ul
  • 200 ul
  • 50 ul

Recombinant Tyrosyl tRNA Synthetase (YARS)

4-RPD003Hu01
  • EUR 476.32
  • EUR 230.00
  • EUR 1511.20
  • EUR 570.40
  • EUR 1040.80
  • EUR 382.00
  • EUR 3628.00
  • 100 ug
  • 10ug
  • 1 mg
  • 200 ug
  • 500 ug
  • 50ug
  • 5 mg
Description: Recombinant Human Tyrosyl tRNA Synthetase expressed in: E.coli

Anti-Tyrosyl tRNA synthetase (2F3)

YF-MA16427 50 ug
EUR 363
Description: Mouse monoclonal to Tyrosyl tRNA synthetase

Anti-Tyrosyl tRNA synthetase (2F3)

YF-MA16428 200 ul
EUR 363
Description: Mouse monoclonal to Tyrosyl tRNA synthetase

100 bp-10 Kb Wide Range DNA Logical Marker, Original Form

M103O-2 5x100loading, 500prep
EUR 363.2

Genomic DNA from hypertension: Heart Atrium, left, from a single donor

D1236126Hd-2 50 ug
EUR 446
Description: Can be used for various studies in the realm of gene expression, both normal and pathological. It is an excellent control and suitable for educational purposes.
In this protocol, we describe a method for aqueous two-phase-assisted precipitation and resolubilization of the recombinant human Granulocyte Colony Stimulating Factor (GCSF) for its selective isolation from E. coli host cell proteins as well as nucleic acids.
This platform purification can be applied to other cytokines as well as most of the hydrophobic proteins that partition into the hydrophobic PEG-rich top phase. Recoveries of up to 100% of the product along with reduction of levels of E. coli host cell proteins (from 250-500 to 10-15 ppm) and of nucleic acids (from 15-20 to 5-15 ng/mL) were observed.

Affinity Tags in Protein Purification and Peptide Enrichment: An Overview

The reversible interaction between an affinity ligand and a complementary receptor has been widely explored in purification systems for several biomolecules. The development of tailored affinity ligands highly specific toward particular target biomolecules is one of the options in affinity purification systems.
However, both genetic and chemical modifications in proteins and peptides widen the application of affinity ligand-tag receptors pairs toward universal capture and purification strategies.
In particular, this chapter will focus on two case studies highly relevant for biotechnology and biomedical areas, namely the affinity tags and receptors employed on the production of recombinant fusion proteins, and the chemical modification of phosphate groups on proteins and peptides and the subsequent specific capture and enrichment, a mandatory step before further proteomic analysis.

Synthetic Ligand Affinity Chromatography Purification of Human Serum Albumin and Related Fusion Proteins

Synthetic ligand affinity adsorbents offer an efficient means for purification of biopharmaceuticals. Single-isomer textile dye C.I. Reactive Blue and newer ligands developed by rational design and screening of chemical combinatorial libraries based on a triazine scaffold are routinely used for the capture and purification of these proteins from engineered recombinant expression systems.
Here, we describe methods for the purification of recombinant human serum albumin and related fusion proteins using synthetic ligand affinity adsorbents.

Redox homeostasis and cell cycle activation mediate beta-cell mass expansion in aged, diabetes-prone mice under metabolic stress conditions: Role of thioredoxin-interacting protein (TXNIP)

 

Overnutrition contributes to insulin resistance, obesity and metabolic stress, initiating a loss of functional beta-cells and diabetes development. Whether these damaging effects are amplified in advanced age is barely investigated.
Therefore, New Zealand Obese (NZO) mice, a well-established model for the investigation of human obesity-associated type 2 diabetes, were fed a metabolically challenging diet with a high-fat, carbohydrate restricted period followed by a carbohydrate intervention in young as well as advanced age.
Interestingly, while young NZO mice developed massive hyperglycemia in response to carbohydrate feeding, leading to beta-cell dysfunction and cell death, aged counterparts compensated the increased insulin demand by persistent beta-cell function and beta-cell mass expansion.
Beta-cell loss in young NZO islets was linked to increased expression of thioredoxin-interacting protein (TXNIP), presumably initiating an apoptosis-signaling cascade via caspase-3 activation. In contrast, islets of aged NZOs exhibited a sustained redox balance without changes in TXNIP expression, associated with higher proliferative potential by cell cycle activation.
These findings support the relevance of a maintained proliferative potential and redox homeostasis for preserving islet functionality under metabolic stress, with the peculiarity that this adaptive response emerged with advanced age in diabetes-prone NZO mice.

GTPBP8 Rabbit pAb

A16189-100ul 100 ul
EUR 308

GTPBP8 Rabbit pAb

A16189-200ul 200 ul
EUR 459

GTPBP8 Rabbit pAb

A16189-20ul 20 ul
EUR 183

GTPBP8 Rabbit pAb

A16189-50ul 50 ul
EUR 223

GTPBP8 Polyclonal Antibody

29768-100ul 100ul
EUR 252

GTPBP8 Polyclonal Antibody

29768-50ul 50ul
EUR 187

Anti-GTPBP8 antibody

STJ118642 100 µl
EUR 277

GTPBP8 cloning plasmid

CSB-CL818697HU1-10ug 10ug
EUR 233
Description: A cloning plasmid for the GTPBP8 gene.

GTPBP8 cloning plasmid

CSB-CL818697HU2-10ug 10ug
EUR 233
Description: A cloning plasmid for the GTPBP8 gene.

Mouse GTPBP8 shRNA Plasmid

20-abx975375
  • EUR 801.00
  • EUR 1121.00
  • 150 µg
  • 300 µg

Rat GTPBP8 shRNA Plasmid

20-abx990090
  • EUR 801.00
  • EUR 1121.00
  • 150 µg
  • 300 µg

Human GTPBP8 shRNA Plasmid

20-abx959177
  • EUR 801.00
  • EUR 1121.00
  • 150 µg
  • 300 µg

GTPBP8 Polyclonal Conjugated Antibody

C29768 100ul
EUR 397

GTPBP8 Recombinant Protein (Rat)

RP203999 100 ug Ask for price

GTPBP8 Recombinant Protein (Human)

RP014239 100 ug Ask for price

GTPBP8 Recombinant Protein (Human)

RP014242 100 ug Ask for price

GTPBP8 Recombinant Protein (Mouse)

RP140480 100 ug Ask for price

GTPBP8 Recombinant Protein (Mouse)

RP140483 100 ug Ask for price

Gtpbp8 ORF Vector (Rat) (pORF)

ORF068001 1.0 ug DNA
EUR 506

Gtpbp8 ORF Vector (Mouse) (pORF)

ORF046828 1.0 ug DNA
EUR 506

Gtpbp8 ORF Vector (Mouse) (pORF)

ORF046829 1.0 ug DNA
EUR 506

GTPBP8 ORF Vector (Human) (pORF)

ORF004747 1.0 ug DNA
EUR 95

GTPBP8 ORF Vector (Human) (pORF)

ORF004748 1.0 ug DNA
EUR 95

cDNA Synthesis SuperMix

20-abx09801420ulSystems
  • EUR 565.00
  • EUR 481.00
  • 100 rxns × 20 ul Systems
  • 50 rxns × 20 ul Systems

Novo? cDNA Kit

M1165-100
EUR 354

Novo? cDNA Kit

M1165-25
EUR 267

Evo? cDNA Supermix

M1168-100
EUR 381

Evo? cDNA Supermix

M1168-25
EUR 267

Novo? cDNA Supermix

M1169-100
EUR 441

Novo? cDNA Supermix

M1169-25
EUR 289

GTPBP8 sgRNA CRISPR Lentivector set (Human)

K0919501 3 x 1.0 ug
EUR 339

Gtpbp8 sgRNA CRISPR Lentivector set (Rat)

K7385901 3 x 1.0 ug
EUR 339

Gtpbp8 sgRNA CRISPR Lentivector set (Mouse)

K4112501 3 x 1.0 ug
EUR 339

cDNA from Plant Normal Tissue: cDNA from Plant: Arabidopsis

C1634310 40 reactions
EUR 621
Description: Can be used for various studies in the realm of gene expression, both normal and pathological. It is an excellent control and suitable for educational purposes.

cDNA from Plant Normal Tissue: cDNA from Plant: Corn

C1634330 40 reactions
EUR 621
Description: Can be used for various studies in the realm of gene expression, both normal and pathological. It is an excellent control and suitable for educational purposes.

cDNA from Plant Normal Tissue: cDNA from Plant: Orange

C1634340 40 reactions
EUR 621
Description: Can be used for various studies in the realm of gene expression, both normal and pathological. It is an excellent control and suitable for educational purposes.

cDNA from Plant Normal Tissue: cDNA from Plant: Potato

C1634350 40 reactions
EUR 621
Description: Can be used for various studies in the realm of gene expression, both normal and pathological. It is an excellent control and suitable for educational purposes.

cDNA from Plant Normal Tissue: cDNA from Plant: Rice

C1634360 40 reactions
EUR 621
Description: Can be used for various studies in the realm of gene expression, both normal and pathological. It is an excellent control and suitable for educational purposes.

cDNA from Plant Normal Tissue: cDNA from Plant: Wheat

C1634390 40 reactions
EUR 621
Description: Can be used for various studies in the realm of gene expression, both normal and pathological. It is an excellent control and suitable for educational purposes.

First-Strand cDNA Synthesis SuperMix (cDNA up to 12 kb)

20-abx09801620ulSystems
  • EUR 620.00
  • EUR 523.00
  • 100 rxns × 20 ul Systems
  • 50 rxns × 20 ul Systems

First-Strand cDNA Synthesis SuperMix (cDNA up to 15 kb)

20-abx09802120ulSystems
  • EUR 871.00
  • EUR 662.00
  • 100 rxns × 20 ul Systems
  • 50 rxns × 20 ul Systems

cDNA from Plant Normal Tissue: cDNA from Plant: Soy bean

C1634370 40 reactions
EUR 621
Description: Can be used for various studies in the realm of gene expression, both normal and pathological. It is an excellent control and suitable for educational purposes.

cDNA Probe Diluent Solution

AR0063 5mL
EUR 106

Tetro cDNA Synthesis Kit

BIO-65042 30 Reactions Ask for price

Tetro cDNA Synthesis Kit

BIO-65043 100 Reactions Ask for price

SensiFAST cDNA Synthesis Kit

BIO-65053 50 Reactions Ask for price

SensiFAST cDNA Synthesis Kit

BIO-65053/S Sample Ask for price

SensiFAST cDNA Synthesis Kit

BIO-65054 250 Reactions Ask for price

Human eNOS cDNA probe

eNOS51-D-2 2 ug
EUR 445

Plant Tissue cDNA: Arabidopsis

PC34-310 10 rxn
EUR 415

OneScriptPlus cDNA Synthesis Kit

G235 25 x 20 ul reactions
EUR 97

OneScriptPlus cDNA Synthesis Kit

G236 100 x 20 ul reactions
EUR 169

OneScriptPlus cDNA Synthesis SuperMix

G453 25 x 20 ul reactions
EUR 97

OneScriptPlus cDNA Synthesis SuperMix

G454 100 x 20 ul reactions
EUR 169

circRNA cDNA Synthesis Kit

G627 25 rxn (20 ul/rxn)
EUR 309

Evo™ cDNA Kit

M1164-100 Ask for price

Evo™ cDNA Kit

M1164-25 Ask for price

Novo? Transcriptome cDNA Kit

M1167-100
EUR 952

Novo? Transcriptome cDNA Kit

M1167-25
EUR 441

cDNA from Arteriosclerosis: Aorta

C1236012Hd-4 40 reactions
EUR 811
Description: Can be used for various studies in the realm of gene expression, both normal and pathological. It is an excellent control and suitable for educational purposes.

cDNA from hypertension: Artery

C1236013Hd-2 40 reactions
EUR 668
Description: Can be used for various studies in the realm of gene expression, both normal and pathological. It is an excellent control and suitable for educational purposes.

cDNA from Arteriosclerosis: Artery

C1236013Hd-4 40 reactions
EUR 811
Description: Can be used for various studies in the realm of gene expression, both normal and pathological. It is an excellent control and suitable for educational purposes.

cDNA from hypertension: Vein

C1236020Hd-2 40 reactions
EUR 668
Description: Can be used for various studies in the realm of gene expression, both normal and pathological. It is an excellent control and suitable for educational purposes.

cDNA from Lupus: Colon

C1236090Lup 40 reactions
EUR 668
Description: Can be used for various studies in the realm of gene expression, both normal and pathological. It is an excellent control and suitable for educational purposes.

cDNA from hypertension: Heart

C1236122Hd-2 40 reactions
EUR 668
Description: Can be used for various studies in the realm of gene expression, both normal and pathological. It is an excellent control and suitable for educational purposes.

cDNA from Lupus: Heart

C1236122Lup 40 reactions
EUR 668
Description: Can be used for various studies in the realm of gene expression, both normal and pathological. It is an excellent control and suitable for educational purposes.

cDNA from hypertension: Kidney

C1236142Hd-2 40 reactions
EUR 668
Description: Can be used for various studies in the realm of gene expression, both normal and pathological. It is an excellent control and suitable for educational purposes.

cDNA from Lupus: Kidney

C1236142Lup 40 reactions
EUR 668
Description: Can be used for various studies in the realm of gene expression, both normal and pathological. It is an excellent control and suitable for educational purposes.

cDNA from Lupus: Liver

C1236149Lup 40 reactions
EUR 668
Description: Can be used for various studies in the realm of gene expression, both normal and pathological. It is an excellent control and suitable for educational purposes.

cDNA from Asthma: Lung

C1236152Ld-1 40 reactions
EUR 811
Description: Can be used for various studies in the realm of gene expression, both normal and pathological. It is an excellent control and suitable for educational purposes.

cDNA from Bronchitis: Lung

C1236152Ld-2 40 reactions
EUR 811
Description: Can be used for various studies in the realm of gene expression, both normal and pathological. It is an excellent control and suitable for educational purposes.

cDNA from Emphysema: Lung

C1236152Ld-3 40 reactions
EUR 811
Description: Can be used for various studies in the realm of gene expression, both normal and pathological. It is an excellent control and suitable for educational purposes.

cDNA from Pneumonia: Lung

C1236152Ld-4 40 reactions
EUR 811
Description: Can be used for various studies in the realm of gene expression, both normal and pathological. It is an excellent control and suitable for educational purposes.

cDNA from Lupus: Lung

C1236152Lup 40 reactions
EUR 668
Description: Can be used for various studies in the realm of gene expression, both normal and pathological. It is an excellent control and suitable for educational purposes.

cDNA from Lupus: Pancreas

C1236188Lup 40 reactions
EUR 668
Description: Can be used for various studies in the realm of gene expression, both normal and pathological. It is an excellent control and suitable for educational purposes.

cDNA from Lupus: Spleen

C1236246Lup 40 reactions
EUR 668
Description: Can be used for various studies in the realm of gene expression, both normal and pathological. It is an excellent control and suitable for educational purposes.

cDNA from Lupus: stomach

C1236248Lup 40 reactions
EUR 668
Description: Can be used for various studies in the realm of gene expression, both normal and pathological. It is an excellent control and suitable for educational purposes.

GTPBP8 sgRNA CRISPR Lentivector (Human) (Target 1)

K0919502 1.0 ug DNA
EUR 154

GTPBP8 sgRNA CRISPR Lentivector (Human) (Target 2)

K0919503 1.0 ug DNA
EUR 154

GTPBP8 sgRNA CRISPR Lentivector (Human) (Target 3)

K0919504 1.0 ug DNA
EUR 154

Gtpbp8 sgRNA CRISPR Lentivector (Rat) (Target 1)

K7385902 1.0 ug DNA
EUR 154

Gtpbp8 sgRNA CRISPR Lentivector (Rat) (Target 2)

K7385903 1.0 ug DNA
EUR 154

Gtpbp8 sgRNA CRISPR Lentivector (Rat) (Target 3)

K7385904 1.0 ug DNA
EUR 154

Gtpbp8 sgRNA CRISPR Lentivector (Mouse) (Target 1)

K4112502 1.0 ug DNA
EUR 154

Gtpbp8 sgRNA CRISPR Lentivector (Mouse) (Target 2)

K4112503 1.0 ug DNA
EUR 154

Gtpbp8 sgRNA CRISPR Lentivector (Mouse) (Target 3)

K4112504 1.0 ug DNA
EUR 154

Gtpbp8 3'UTR GFP Stable Cell Line

TU255567 1.0 ml Ask for price

GTPBP8 3'UTR Luciferase Stable Cell Line

TU009450 1.0 ml
EUR 1394

Gtpbp8 3'UTR GFP Stable Cell Line

TU159227 1.0 ml Ask for price

Gtpbp8 3'UTR Luciferase Stable Cell Line

TU205567 1.0 ml Ask for price

GTPBP8 3'UTR GFP Stable Cell Line

TU059450 1.0 ml
EUR 1394

Gtpbp8 3'UTR Luciferase Stable Cell Line

TU109227 1.0 ml Ask for price

GTPBP8 Protein Vector (Human) (pPB-C-His)

PV018985 500 ng
EUR 329

GTPBP8 Protein Vector (Human) (pPB-N-His)

PV018986 500 ng
EUR 329

GTPBP8 Protein Vector (Human) (pPM-C-HA)

PV018987 500 ng
EUR 329

GTPBP8 Protein Vector (Human) (pPM-C-His)

PV018988 500 ng
EUR 329

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